Results 71 to 80 of about 2,781 (260)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Variable DC voltage based reactive power enhancement scheme for MMC‐STATCOM

open access: yesIET Smart Grid
Constrained by the AC voltage amplitude modulated by a modular multilevel converter‐based static synchronous compensator (MMC‐STATCOM), its reactive power output may be subject to oscillations under grid contingencies, posing a threat to the grid stable ...
Lujie Yu   +4 more
doaj   +1 more source

DC voltage margin adaptive droop control strategy of VSC-MTDC systems

open access: yesThe Journal of Engineering, 2019
In this study, direct current (DC) voltage margin control strategy and droop control strategy of voltage source converter multi-terminal direct current (VSC-MTDC) are introduced firstly, and according to the characteristics of two control strategies, an ...
Zhi Ping Cheng   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Analysis of DC voltage oscillation mechanism in AC/DC hybrid distribution system

open access: yesThe Journal of Engineering, 2019
DC voltage oscillation occurs more and more frequently in voltage source converter (VSC)-based AC/DC hybrid distribution system (AC/DC HDS). However, currently, the explanation of the oscillation mechanism is not clear enough.
Luyang Li   +4 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Parallel current-controlled synchronverters for voltage and frequency regulation in weak grids

open access: yesThe Journal of Engineering, 2019
The emulation of synchronous machines is becoming an attractive solution to provide virtual inertia and voltage support to weak grids and microgrids, representing an alternative to conventional current-injection control strategies.
Javier Roldán-Pérez   +2 more
doaj   +1 more source

Testing of Liquid Metal Components for Nuclear Surface Power Systems [PDF]

open access: yes, 2010
The capability to perform testing at both the module/component level and in near prototypic reactor configurations using a non-nuclear test methodology allowed for evaluation of two components critical to the development of a potential nuclear fission ...
Adkins, H. E.   +8 more
core   +1 more source

Potentialities of TEC topping: A simplified view of parametric effects [PDF]

open access: yes, 1980
An examination of the benefits of thermionic-energy-conversion (TEC)-topped power plants and methods of increasing conversion efficiency are discussed. Reductions in the cost of TEC modules yield direct decreases in the cost of electricity (COE) from TEC-
Morris, J. F.
core   +2 more sources

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

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