Results 71 to 80 of about 4,139,374 (252)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Variable DC voltage based reactive power enhancement scheme for MMC‐STATCOM

open access: yesIET Smart Grid
Constrained by the AC voltage amplitude modulated by a modular multilevel converter‐based static synchronous compensator (MMC‐STATCOM), its reactive power output may be subject to oscillations under grid contingencies, posing a threat to the grid stable ...
Lujie Yu   +4 more
doaj   +1 more source

DC voltage margin adaptive droop control strategy of VSC-MTDC systems

open access: yesThe Journal of Engineering, 2019
In this study, direct current (DC) voltage margin control strategy and droop control strategy of voltage source converter multi-terminal direct current (VSC-MTDC) are introduced firstly, and according to the characteristics of two control strategies, an ...
Zhi Ping Cheng   +3 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Loss comparison of 2 and 3-level inverter topologies

open access: yes, 2010
This paper investigates semiconductor and DC-link capacitor losses in two two-level and two three-level voltage source inverters. The components of the four inverters are selected to have appropriate voltage and current ratings.
Orfanoudakis, G.   +3 more
core   +1 more source

Weak Coupling Effects in the PLL Modes of Grid‐Following PMSG Wind Power Systems

open access: yesIET Renewable Power Generation
Small‐signal synchronisation stability is a critical issue of grid‐connected permanent magnet synchronous generator (PMSG) wind power systems employing grid‐following voltage source converters (VSCs).
Xumeng Cui   +5 more
doaj   +1 more source

Analysis of DC voltage oscillation mechanism in AC/DC hybrid distribution system

open access: yesThe Journal of Engineering, 2019
DC voltage oscillation occurs more and more frequently in voltage source converter (VSC)-based AC/DC hybrid distribution system (AC/DC HDS). However, currently, the explanation of the oscillation mechanism is not clear enough.
Luyang Li   +4 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Parallel current-controlled synchronverters for voltage and frequency regulation in weak grids

open access: yesThe Journal of Engineering, 2019
The emulation of synchronous machines is becoming an attractive solution to provide virtual inertia and voltage support to weak grids and microgrids, representing an alternative to conventional current-injection control strategies.
Javier Roldán-Pérez   +2 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

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