Selective posttranslational inhibition of CaVβ1-associated voltage-dependent calcium channels with a functionalized nanobody [PDF]
, 2022 Travis J. Morgenstern +10 more
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FoodsArterial hypertension is a highly prevalent chronic disease worldwide, with several etiologies and treatments that may eventually have side effects or result in patients developing tolerance.
Yadira Ramírez-Rodríguez +11 more
doaj +1 more source
Prophylactic Management of Vestibular Migraine: A Systematic Review
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Vestibular migraine (VM) is a neurological disorder characterized by episodic vertigo in patients with migraine, contributing to substantial functional impairment. Although VM is relatively common, a consensus on effective prophylactic treatments is lacking.
Hussain Ali Almohammed +11 more
wiley +1 more source
Multiple Structural Domains Contribute to Voltage-dependent Inactivation of Rat Brain α1E Calcium Channels [PDF]
, 1999 Renee Spaetgens, Gerald W. Zamponi
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Recent advances in our understanding of the structure and function of more unusual cation channels. [PDF]
, 2019 As their name implies, cation channels allow the regulated flow of cations such as sodium, potassium, calcium, and magnesium across cellular and intracellular membranes.
Brown, Brandon M +2 more
core +1 more source
Large conductance Ca2+-activated K+ (BK) channel: Activation by Ca2+ and voltage
Biological Research, 2006 Large conductance Ca2+-activated K+ (BK) channels belong to the S4 superfamily of K+ channels that include voltage-dependent K+ (Kv) channels characterized by having six (S1-S6) transmembrane domains and a positively charged S4 domain. As Kv channels, BK
RAMÓN LATORRE, SEBASTIAN BRAUCHI
doaj
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan +22 more
wiley +1 more source
Identification of structural elements of the testis-specific voltage dependent calcium channel that potentially regulate its biophysical properties [PDF]
, 1999 Leslie O. Goodwin
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The Stargazin-Related Protein {gamma}7 Interacts with the mRNA-Binding Protein Heterogeneous Nuclear Ribonucleoprotein A2 and Regulates the Stability of Specific mRNAs, Including CaV2.2 [PDF]
, 2008 The role(s) of the novel stargazin-like {gamma}-subunit proteins remain controversial. We have shown previously that the neuron-specific {gamma}7 suppresses the expression of certain calcium channels, particularly CaV2.2, and is therefore unlikely to ...
Bolsover, Steven +11 more
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Arthritis Care &Research, Accepted Article.Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart +14 more
wiley +1 more source