Results 141 to 150 of about 248,505 (393)
Involvement of Protein Kinase C and Protein Kinase A in the Enhancement of L-type Calcium Current by GABA\u3csub\u3eB\u3c/sub\u3e Receptor Activation in Neonatal Hippocampus [PDF]
In the early neonatal period activation of GABAB receptors attenuates calcium current through N-type calcium channels while enhancing current through L-type calcium channels in rat hippocampal neurons.
Bray, Jennifer Grace, Mynlieff, Michelle
core +1 more source
Patient‐specific brain phantoms can replace animal trials, aid presurgical training, and enable in silico disease research on cerebrospinal fluid and ventricles. This study presents a method to create ventricular brain phantoms from three‐dimensional magnetic resonance images brain scans, resulting in durable, tunable, reproducible models that mimic ...
Kajal Chandraprakash Jain+3 more
wiley +1 more source
Arterial hypertension is a highly prevalent chronic disease worldwide, with several etiologies and treatments that may eventually have side effects or result in patients developing tolerance.
Yadira Ramírez-Rodríguez+11 more
doaj +1 more source
Novel charged sodium and calcium channel inhibitor active against neurogenic inflammation
Voltage-dependent sodium and calcium channels in pain-initiating nociceptor neurons are attractive targets for new analgesics. We made a permanently charged cationic derivative of an N-type calcium channel-inhibitor.
Seungkyu Lee+14 more
doaj +1 more source
MECHANISMS OF DISEASE Acute Oxygen-Sensing Mechanisms [PDF]
JOSEPH PRIESTLEY, ONE OF THE THREE SCIENTISTS CREDITED WITH THE discovery of oxygen, described the death of mice that were deprived of oxygen. However, he was also well aware of the toxicity of too much oxygen, stating, “For as a candle burns much faster
Buckler, Keith J.+3 more
core
This review explores wafer bonding technologies, covering wafer preparation, activation methods, and bonding mechanisms. It compares direct and indirect bonding, highlights recent advancements and future trends, and examines applications in 3D integration and packaging.
Abdul Ahad Khan+5 more
wiley +1 more source
Surface Modification of Sol–Gel Synthesized Ba0.85Ca0.15Zr0.1Ti0.9O3 using Stearic Acid Additives
This study explores a novel approach to enhance the piezoelectric performance of lead‐free BCZT ceramics synthesized via the sol–gel method. By coating the BCZT powder with only a 0.69 nm stearic acid layer, the electromechanical response is significantly boosted up to 359 pC N−1, revealing promising implications for high‐performance sensor and ...
Michelle Weichelt+6 more
wiley +1 more source
A highly stable, low‐temperature phosphate glass is developed for multimaterial additive manufacturing of multifunctional microfluidics. Glass, metal conductors, and sacrificial polymer are coprinted, enabling monolithic fabrication. The sacrificial paste forms precise channels and decomposes during sintering.
Babak Mazinani+2 more
wiley +1 more source
Large conductance Ca2+-activated K+ (BK) channel: Activation by Ca2+ and voltage
Large conductance Ca2+-activated K+ (BK) channels belong to the S4 superfamily of K+ channels that include voltage-dependent K+ (Kv) channels characterized by having six (S1-S6) transmembrane domains and a positively charged S4 domain. As Kv channels, BK
RAMÓN LATORRE, SEBASTIAN BRAUCHI
doaj
Designer genetically encoded voltage-dependent calcium channel inhibitors inspired by RGK GTPases. [PDF]
Colecraft HM.
europepmc +1 more source