Results 51 to 60 of about 2,776 (262)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Stirling Convertor Controller Development at NASA Glenn Research Center [PDF]
For nearly two decades, NASA Glenn Research Center (GRC) has been supporting the development of Radioisotope Power Systems (RPS). NASA desires higher conversion efficiency RPS options that are reliable and robust with long life design. Dynamic conversion,
Dugala, Gina M.
core +4 more sources
IET Power ElectronicsTo solve the commutation failure (CF) issues in high voltage direct current (HVDC) transmission systems based on line commutated converter (LCC), this paper proposes a hybrid solution combining the LCC inverter with the continuously controlled IGCT‐based
Yindi Liu +3 more
doaj +1 more source
Novel protection method for VSC-HVDC transmission lines
The Journal of Engineering, 2019 The large shunt capacitances on both sides of VSC-HVDC transmission line will block and reflect the travelling waves when a fault occurs on DC cable lines.
Lingtong Jiang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Control scheme for multi-terminal VSC-based medium-voltage DC distribution networks
The Journal of Engineering, 2019 With the development and application of voltage source converter (VSC) high voltage direct current (HVDC) technology, DC distribution is gradually attracting the attention of researchers in recent years. However, many studies are still in the theoretical
Yirun Ji +6 more
doaj +1 more source
Control of Dual-Opposed Stirling Convertors with Active Power Factor Correction Controllers [PDF]
, 2006 When using recently-developed active power factor correction (APFC) controllers in power systems comprised of dual-opposed free-piston Stirling convertors, a variety of configurations of the convertors and controller(s) can be considered, with ...
Lewandowski, Edward J. +2 more
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Comparison of DC linear and non-linear models for multi-terminal VSC HVDC networks
The Journal of Engineering, 2019 The analysis and control design of multi-terminal VSC-HVDC systems requires a linearised model of these inherently non-linear systems. This paper develops such a model, from converter to multi-terminal system, discusses the key concepts and shows its use
Jesus Carmona-Sanchez +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source