Results 81 to 90 of about 2,509,073 (379)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

High Voltage Generation for Physics Lab [PDF]

open access: yesarXiv, 2012
A power efficient way to generate low power high voltage is given. The article describes various aspects of functioning and derives quantitative relations between different parameters and high voltage generated. Use of voltage multiplier (Cockcroft-Walton multiplier) network can provide further boost in the high voltage(~1000V).
arxiv  

On the Impact of Different Voltage Unbalance Metrics in Distribution System Optimization [PDF]

open access: yesarXiv, 2020
With increasing penetrations of single-phase, rooftop solar PV installations, the relative variations in per-phase loading and associated voltage unbalance are expected to increase. High voltage unbalance may increase network losses and lead to failure of three-phase equipment such as motor loads.
arxiv  

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

A hybrid multilevel converter for medium and high voltage applications [PDF]

open access: yes, 2010
This paper investigates the suitability of the hybrid multilevel converter for medium and high voltage application. The converter operation, modulation, and capacitor voltage balancing method are described in detail.
Adam, Grain Philip   +4 more
core  

Flying-capacitor multilevel converter voltage balance dynamics for pure resistive load [PDF]

open access: yes, 2009
Multilevel converters need voltage balancing to be able to generate an output voltage with high quality. Flying capacitor converter topology has a natural voltage balancing property.
Melkebeek, Jan   +2 more
core   +2 more sources

Heat‐pump performance: voltage dip/sag, under‐voltage and over‐voltage

open access: yesThe Journal of Engineering, 2014
Reverse cycle air‐source heat‐pumps are an increasingly significant load in New Zealand and in many other countries. This has raised concern over the impact wide‐spread use of heat‐pumps may have on the grid. The characteristics of the loads connected to the power system are changing because of heat‐pumps.
Neville R. Watson   +2 more
openaire   +3 more sources

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Multi‐view synergistic enhanced fault recording data for transmission line fault classification

open access: yesIET Communications
Fault recorded data has been proven to be effective for fault diagnosis of overhead transmission lines. Utilizing deep learning to mine potential fault patterns in fault recording data is an inevitable trend.
Minghui Jia   +9 more
doaj   +1 more source

Smart UAV Infrared Image Defect Detection using YOLOv3 and Gaussian Mixture Models

open access: yesTehnički Vjesnik
To improve detection performance, a model with strong universality and adaptability to different environments was established. This study proposed a migration and optimization method for drone infrared image defect detection and recognition models based ...
Rong Meng   +4 more
doaj   +1 more source

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