Results 81 to 90 of about 4,141,576 (334)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Federated knowledge distillation for enhanced insulator defect detection in resource‐constrained environments

IET Computer Vision
Insulator defect detection is crucial for the stable operation of power systems. It has become a mainstream research direction to realise insulator defect detection based on the combination of line images captured by UAVs and deep learning techniques ...
Xiaohu Huang, Minghui Jia, Xianghua Tai, Wei Wang, Qi Hu, Dongping Liu, Peiheng Guo, Shengxiang Tian, Dequan Yan, Haishan Han   +9 more
doaj   +1 more source

Distributed Control of Battery Energy Storage Systems for Voltage Regulation in Distribution Networks With High PV Penetration

IEEE Transactions on Smart Grid, 2018
The voltage rise problem in low voltage distribution networks with high penetration of photovoltaic (PV) resources is one of the most important challenges in the development of these renewable resources since it may prevent the maximum PV penetration ...
M. Zeraati, M. E. Hamedani Golshan, J. Guerrero   +2 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Distribution Optimization Method for Power Environment-Friendly Mixed Insulation Gas

Zhongguo dianli
The state-of-art cost of environmental-friendly SF6/CF4 mixed insulating gas of GIS equipment in the power system is relatively high. In order to ensure its insulation and arc extinguishing performance, SF6 gas is overfilled on site, which is not in line
Jie DONG, Bo YANG, Guoxin YI, Haichuan HE, Le MA   +4 more
doaj   +1 more source

Powerplexer [PDF]

, 1973
An electrical power distribution system is described for use in providing different dc voltage levels. A circuit is supplied with DC voltage levels and commutates pulses for timed intervals onto a pair of distribution wires.
Woods, J. M.
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Arc lamp power supply using a voltage multiplier [PDF]

, 1988
A power supply is provided for an arc discharge lamp which includes a relatively low voltage high current power supply section and a high voltage starter circuit.
Leighty, Bradley D.
core   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

FEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii, Edoardo Andrea Cutolo, Daniele Montepietra, Claudia Battarra, Roberto Caferri, Stefano Capaldi, Zeno Guardini, Luca Dall'Osto, Roberto Bassi   +8 more
wiley   +1 more source