Results 81 to 90 of about 126,199 (290)
CalFUSE v3: A Data-Reduction Pipeline for the Far Ultraviolet Spectroscopic Explorer
Since its launch in 1999, the Far Ultraviolet Spectroscopic Explorer (FUSE) has made over 4600 observations of some 2500 individual targets. The data are reduced by the Principal Investigator team at the Johns Hopkins University and archived at the ...
A. W. Fullerton +16 more
core +2 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Passivity‐Based Control of Quadratic Boost Converter: An Experimental Case Study
This paper introduces a high‐gain voltage quadratic boost converter (QBC) and for control presents a non‐linear control method based on introduction and damping assignment passivity based control (IDA‐PBC) to regulate it.
Abdollah Ahmadi +3 more
doaj +1 more source
Device-spectroscopy of magnetic field effects in a polyfluorene organic light-emitting diode
We perform charge-induced absorption and electroluminescence spectroscopy in a polyfluorene organic magnetoresistive device. Our experiments allow us to measure the singlet exciton, triplet exciton and polaron densities in a live device under an applied ...
B. Movaghar +6 more
core +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Sparse Automatic Differentiation for Large-Scale Computations Using Abstract Elementary Algebra
Most numerical solvers and libraries nowadays are implemented to use mathematical models created with language-specific built-in data types (e.g. real in Fortran or double in C) and their respective elementary algebra implementations.
Klus, Stefan, Peles, Slaven
core
Stack Aware Threshold Voltage Assignment in 3-D Multicore Designs
Due to the inherent nature of heat flow in 3-D integrated circuits, stacked dies exhibit a wide range of thermal characteristics. The temperature of dies progressively increases with increasing distance from the heat sink. This heterogeneous temperature profile coupled with the strong dependence of leakage on temperature and process variation plays ...
Chakraborty, Koushik, Roy, Sanghamitra
openaire +3 more sources
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Voltage island-aware multiple voltage assignment based on genetic algorithm(基于遗传算法的电压岛感知的多电压分配)
功耗是当前SoC设计所面临的最大挑战之一,多电压设计是一种降低SoC芯片功耗的有效方法.在后布局阶段应用多电压设计,首先对现有电源网络复杂性度量方法进行改进,然后提出了一个同时考虑功耗、电源网络复杂性及电平转换器的新目标函数,并采用遗传算法进行最优电压分配.对GSRC测试电路的实验结果表明,所提出的算法不仅能有效降低芯片功耗,同时可以将多电压设计的额外开销控制在一个较低的水平.此外,改进的电源网络复杂性度量方法在功耗节省和电平转换器数量方面较已有的有一定的优势.
DUShi-min(杜世民) +2 more
doaj +1 more source

