Results 101 to 110 of about 126,199 (290)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Decentralized Control of DC Microgrids Using Interconnection and Damping Assignment Passivity-Based Control Technique: Experimental Verification

IEEE Access
A decentralized control approach is introduced in this paper that utilizes passivity-based control for two DC-distributed energy sources supplying the power of a load. Considering the concept of passivity, if each distributed generator exhibits passivity,
Mohammad Afkar, Cong Yuan, Roghayeh Gavagsaz-Ghoachani, Wiset Saksiri, Matheepot Phattanasak, Jean-Philippe Martin, Serge Pierfederici   +6 more
doaj   +1 more source

Do Customers Choose Proper Tariff? Empirical Analysis Based on Polish Data Using Unsupervised Techniques

Energies, 2018
Individual electricity customers that are connected to low voltage network in Poland are usually assigned to the most common G11 tariff group with flat prices for the whole year, no matter the usage volume.
Rafik Nafkha, Krzysztof Gajowniczek, Tomasz Ząbkowski   +2 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Shunt active power filter using model predictive control with stability guarantee

e-Prime: Advances in Electrical Engineering, Electronics and Energy
This paper presents a model predictive control (MPC) strategy to solve an optimization problem based on system state and control variables, subject to constraints imposed by the control objective.
Jhon Pérez-Ramírez, Diego Montoya-Acevedo, Walter Gil-González, Oscar Danilo Montoya, Carlos Restrepo   +4 more
doaj   +1 more source

Observations on the construction of covers using permutation voltage assignments

Discrete Mathematics, 1979
AbstractIn the usual treatment of covering spaces, the algebraic object associated with a cover is a conjugacy class of subgroups of the fundamental group of the target space. For finite degree covers, one could as easily choose the algebraic object to be a class of homomorphisms from the fundamental group of the target space to the symmetric group on ...
openaire   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Parametric Yield-Driven Resource Binding in High-Level Synthesis with Multi-Vth/Vdd Library and Device Sizing

Journal of Electrical and Computer Engineering, 2012
The ever-increasing chip power dissipation in SoCs has imposed great challenges on today’s circuit design. It has been shown that multiple threshold and supply voltages assignment (multi-Vth/Vdd) is an effective way to reduce power dissipation.
Yibo Chen, Yu Wang, Yuan Xie, Andres Takach   +3 more
doaj   +1 more source

Development of an Optimal Power Control Scheme for Wave-Offshore Hybrid Generation Systems

Energies, 2015
Integration technology of various distribution systems for improving renewable energy utilization has been receiving attention in the power system industry.
Seungmin Jung, Gilsoo Jang
doaj   +1 more source