Results 181 to 190 of about 1,452,967 (344)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Dataset for the manuscript "Low-Voltage Controlled Coercivity in Nanocrystalline Fe-Ni Films by Magneto-Ionic Effects"

Ullrich, Anna, Hambeck, Florin Leo, Kohlstedt, Raphael, Sgarbi Stabellini, Francesca, Schiemenz, Sandra, Wolf, Daniel, Leistner, Karin   +6 more
openalex   +1 more source

Fault-Tolerant Control of Cascaded H-Bridge Converters Using Double Zero-Sequence Voltage Injection and DC Voltage Optimization [PDF]

, 2014
Zhendong Ji, Jianfeng Zhao, Yichao Sun, Xiaojun Yao, Zean Zhu   +4 more
openalex   +1 more source

Consensus-based Distributed Bus Voltage Control of in DC Microgrid Clusters

, 2023
Ci Chen, Min Zheng, Yajian Zhang, Chen Peng, Fei Xue   +4 more
openalex   +1 more source

High-Impulse, Modular, 3D-Printed CubeSat Electrospray Thrusters Throttleable via Pressure and Voltage Control. [PDF]

Adv Sci (Weinh)
Kim H, Velásquez-García LF.
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Graph-Based Topological Embedding and Deep Reinforcement Learning for Autonomous Voltage Control in Power System. [PDF]

Sensors (Basel)
Wei H, Chang S, Zhang J.
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Voltage Control for a Loop Distribution System with Renewable Energy Sources

, 2010
Yuki Hanai, Yasuhiro Hayashi, Junya Matsuki   +2 more
openalex   +1 more source

Smart Loads for Voltage Control in Distribution Networks [PDF]

, 2015
Zohaib Akhtar, Balarko Chaudhuri, S.Y.R. Hui   +2 more
openalex   +1 more source