Results 101 to 110 of about 1,683 (291)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Passive Harmonic RFID System for Buried Assets Localization
Sensors, 2018 A passive harmonic tag for buried assets localization is presented for utility localization. The tag design is based on a dual-polarized patch antenna at Ultra High Frequency (UHF) band.
Abanob Abdelnour +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Dual-band low-power RF-to-DC signal converter circuits for energy harvesting
AIP AdvancesThis article presents dual-band low-power, high-sensitive radio-frequency (RF)-to-direct current (DC) signal converter circuits, operating at 2.45 and 5.5 GHz bands, for radio frequency energy harvesting applications.
Pavan Mehta, Anveshkumar Nella
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A 82% Efficiency 0.5% Ripple 16-Phase Fully Integrated Capacitive Voltage Doubler
, 2009 A fully integrated voltage doubler is presented. Using a 16-phase switching strategy, the output voltage ripple is reduced to less then 0.5% of the output voltage.
Steyaert, Michel, Van Breussegem, Tom
core
Família de retificadores PWM unidirecionais três-níveis híbridos a capacitor chaveado com elevado fator de potência [PDF]
, 2015 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2015.Esta tese de doutorado tem por objetivo a proposta de uma nova família de conversores ca-cc três níveis ...
Cortez, Daniel Flores
core
, 2009 Single phase full bridge inverter with coupled filter inductors and voltage doubler for PV module integrated converter systemThis paper presents a single phase full bridge inverter with coupled filter inductors and voltage doubler for PV module ...
Y. Jiang, J. Pan
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source