Results 121 to 130 of about 3,524,493 (338)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Improved circuit for measuring capacitive and inductive reactances [PDF]
, 1967 Amplifier circuit measures very small changes of capacitive or inductive reactance, such as produced by a variable capacitance or a variable inductance displacement transducer.
Dalins, I., Mc Carty, V.
core +1 more source
Dual-band low-power RF-to-DC signal converter circuits for energy harvesting
AIP AdvancesThis article presents dual-band low-power, high-sensitive radio-frequency (RF)-to-direct current (DC) signal converter circuits, operating at 2.45 and 5.5 GHz bands, for radio frequency energy harvesting applications.
Pavan Mehta, Anveshkumar Nella
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Explorer Satellite Electronics [PDF]
, 1960 A discussion is presented of the design restrictions and the philosophy which enabled the Explorer satellites to be first during the IGY to reveal the presence of a belt of intense cosmic radiation encircling the earth's equator.
Eyraud, J. P. +2 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Wide-band doubler and sine wave quadrature generator [PDF]
, 1969 Phase-locked loop with photoresistive control, which provides both sine and cosine outputs for subcarrier demodulation, serves as a telemetry demodulator signal conditioner with a second harmonic signal for synchronization with the locally generated ...
Crow, R. B.
core +1 more source
Research and Modeling of the Bidirectional Half-Bridge Current-Doubler DC/DC Converter
International Journal of Rotating Machinery, 2017 Due to its high step-up voltage ratio, high utilization rate, and good stability, the bidirectional half-bridge current-doubler topology is widely used in lithium battery system.
Liang Huang +4 more
doaj +1 more source