Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
FEBS Open Bio, EarlyView.Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
Coherent communication link using diode-pumped lasers [PDF]
Work toward developing a diffraction limited, single frequency, modulated transmitter suitable for coherent optical communication or direct detection communication is discussed.
Kane, Thomas J., Wallace, Richard W.
core +1 more source
A High-Power 170 GHz in-Phase Power-Combing Frequency Doubler Based on Schottky Diodes. [PDF]
Micromachines (Basel), 2023 Wang L, Zhang D, Meng J, Zhu H.
europepmc +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
Development of an optimized second harmonic generator cell Final scientific report, 12 Jun. 1969 - 12 Mar. 1970 [PDF]
Optimized second harmonic generator ...
Bass, M.
core +1 more source
Gyroklistron - frequncy multipliers
Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2016 The results of a three-stage gyroklystron - frequency doubler are shown. It is shown that at an gyroklystron output frequency 95 GGz, beam voltage 126.5 kV, current 29.5 A and the correct choice of the resonator Q , their offsets from the operating ...
S. V. Kolosov
doaj
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
An Adaptive Reconfigurable Active Voltage Doubler/Rectifier for Extended-Range Inductive Power Transmission. [PDF]
IEEE Trans Circuits Syst II Express Briefs, 2012 Lee HM, Ghovanloo M.
europepmc +1 more source