Results 131 to 140 of about 163,690 (311)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hybrid Control Switching Technology for LLC Resonant Converter

open access: yesEnergies
Aiming at the problem of the circuit operating frequency changing beyond the regulation range and zero switching not being guaranteed when the input voltage range of the LLC resonant converter is large, a hybrid control technology with a variable ...
Jie Zhang, Zhixiao Cai
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Switched-capacitor Based Seven-level Boost Inverter with a Reduced Number of Devices

open access: yesCSEE Journal of Power and Energy Systems
The conventional multilevel inverters (MLIs) have the disadvantages of numerous devices, incapacity of boost, unbalance for capacitor's voltage, high complexity for control, and etc.
Weijie Lin   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

PV microinverter solution for high voltage gain and soft switching

open access: yes, 2021
This paper proposes a high-gain flyback type microinverter for PV power generation. The proposed topology integrates a voltage-doubler circuit with the flyback converter to produce the high voltage-conversion gain.
Xiao, W (15587453)   +2 more
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Modular nine-level single-phase inverter with quadruple voltage gain using reduced blocking voltage switches [PDF]

open access: yes
Funding Information: This work was supported by national funds through UnIRE, ISEL, Polytechnic University of Lisboa and FCT Fundação para a Ciência e a Tecnologia with reference UIDB/50021/2020 and UIDB/00066/2020.0.1109/PESC.2008.4591920. Publisher
Cordeiro, Armando   +5 more
core   +1 more source

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