Results 121 to 130 of about 678,734 (304)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Compensated control loops for a 30-cm ion thruster [PDF]
The vaporizer dynamic control characteristics of a 30-cm diameter mercury ion thruster were determined by operating the thruster in an open loop steady state mode and then introducing a small sinusoidal signal on the main, cathode, or neutralizer ...
Robson, R. R.
core +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Research of the Common-mode Voltage Inhibition for Three-level NPC Inverter
Kongzhi Yu Xinxi Jishu, 2015 Adopting NPC(Neutral Point Clamped) three-level inverters as a research object, it analyzed three control strategies for common-mode voltage inhibition, such as traditional three -level SVPWM, SVPWM for reducing common-mode voltage and SVPWM for ...
DING Guanyuan, LI Yinling, LI Kai
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Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
International Journal of Electrical Power & Energy SystemsThe increased demand for renewable energy and electrification of transportation such as electric vehicles can lead to power quality problems in the low voltage distribution grids.
Dimitar V. Bozalakov +3 more
doaj +1 more source
Fast control technique for high frequency (5MHz) DC/DC integrated converter [PDF]
, 2010 A switching frequency of 5 MHz allows the integration in a chip of a low power (10W) DC/DC converter. Although this switching frequency would make feasible a voltage mode control with 1MHz bandwidth, the parasitics and robustness don't allow such a high ...
Alou Cervera, Pedro +4 more
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