Results 41 to 50 of about 33,314 (300)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

High Step-Up Interleaved DC/DC Converter Using VM Cell for PV Applications [PDF]

open access: yesIranian Journal of Electrical and Electronic Engineering, 2022
This work proposes a high step-up interleaved dc/dc topology utilizing a VM (voltage multiplier) cell suitable for PV applications. The VM cells D/C (Diode/Cap.) are cascaded among the phases to approach a high voltage gain.
Amir Gallaj   +2 more
doaj  

A 64-point Fourier transform chip for high-speed wireless LAN application using OFDM

open access: yes, 2004
In this article, we present a novel fixed-point 16-bit word-width 64-point FFT/IFFT processor developed primarily for the application in the OFDM based IEEE 802.11a Wireless LAN (WLAN) baseband processor.
Grass, Eckhard   +2 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Asymmetrical Interleaved DC/DC Switching Converters for Photovoltaic and Fuel Cell Applications—Part 1: Circuit Generation, Analysis and Design

open access: yesEnergies, 2012
A novel asymmetrical interleaved dc/dc switching converters family intended for photovoltaic and fuel cell applications is presented in this paper. The main requirements on such applications are small ripples in the generator and load, as well as high ...
Sergio Serna   +4 more
doaj   +1 more source

Design of a CMOS closed-loop system with applications to bio-impedance measurements [PDF]

open access: yes, 2010
This paper proposes a method for impedance measurements based on a closed-loop implementation of CMOS circuits. The proposed system has been conceived for alternate current excited systems, performing simultaneously driving and measuring functions ...
Rueda Rueda, Adoración   +1 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Interleaved step-up soft-switching DC–DC Boost converter without auxiliary switches

open access: yesEnergy Reports, 2022
A voltage gain interleaved soft switched DC–DC Boost converter without auxiliary switch is proposed in this paper. Step-up characteristics are achieved without using any transformer, coupled inductor, voltage multiplier cell, switched inductor/switched ...
M. Rezvanyvardom   +6 more
doaj   +1 more source

Development of Urban Electric Bus Drivetrain [PDF]

open access: yes, 2019
The development of the drivetrain for a new series of urban electric buses is presented in the paper. The traction and design properties of several drive variants are compared.
Chyský J.   +5 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy