Results 121 to 130 of about 2,515,031 (212)

Affects of TCSC usages on Distance protection and Voltage profile of a system ; a novel

, 2011
TCSCs are used in power systems to improve the profile of Voltage, flexibility and overall power flow capacity of power systems. The basic concept of TCSC usages is that by changing transmission line's impedance, increasing the power transfer capability ...
Jahdi, Saeed, Lei Lai, Loi, null Loi Lei Lai, Saeed Jahdi, Lai, Loi Lei   +4 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Minimizing Voltage Deviations by Using Optimal Volt/VAr Curves Dynamic Control in Smart Inverters for Photovoltaic Installations

IEEE Open Access Journal of Power and Energy
This research paper proposes a new method to improve per unit voltage (V ${}_{\mathrm {pu}}$ ) control in electrical energy distribution systems (EEDS) through the appropriate injection or absorption of reactive power (Q) from photovoltaic smart ...
F. Javier Alcantara, Rolando Baldeon Orellana, Hubel Gonzalo Valderrama, Jesus R. Vazquez   +3 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Optimum placement of multi type DG units for loss reduction in a radial distribution system considering the distributed generation [PDF]

Bulletin of the Polish Academy of Sciences: Technical Sciences, 2018
J. Shanmugapriyan, N. Karuppiah, S. Muthubalaji, S. Tamilselvi   +3 more
doaj   +1 more source

Optimal design and analysis of a grid‐connected hybrid renewable energy system using HOMER Pro: A case study of Tumbatu Island, Zanzibar

Energy Science & Engineering
This study addresses the pressing issue of quality electricity access in remote regions, with a specific focus on Tumbatu Island in Tanzania. Most studies on quality improvement concentrate on low‐voltage distribution lines and leave high‐voltage (HV ...
Thani R. Said, Baraka Kichonge, Thomas Kivevele   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Improving Voltage Stability Margin Using Voltage Profile and Sensitivity Analysis by Neural Network

, 2011
This paper presents a new approach for estimating and improving voltage stability margin from phase and magnitude profile of bus voltages using sensitivity analysis of Voltage Stability Assessment Neural Network (VSANN).
S. S. Hashemi, M. Aghamohammadi, M. S. Ghazizadeh   +2 more
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source