Results 101 to 110 of about 204,898 (264)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
A Tool for Synthesizing and Implementing Medium Voltage Load Profiles
To support energy planning and grid investigations, this paper presents an open source tool to generate and integrate realistic synthetic load profiles (SLPs) into power system software. The tool assigns daily SLPs to all loads within a network and is compatible with Vision Network Analysis and OpenDSS.
Hendrik Plompen +5 more
openaire +1 more source
CONTROL AND OPTIMIZATION OF VOLTAGE PROFILES AND SAG MITIGATION IN LOW-VOLTAGE POWER NETWORKS
REVUE ROUMAINE DES SCIENCES TECHNIQUES — SÉRIE ÉLECTROTECHNIQUE ET ÉNERGÉTIQUEVoltage sags, swells, and fluctuations in low-voltage networks can disrupt sensitive equipment, reduce industrial productivity, and accelerate component aging. This paper reviews common assessment practices, including ITIC/CBEMA curves and waveform analysis, and proposes an enhanced method that also considers pre- and post-event intervals to better ...
GABRIEL IOANA +2 more
openaire +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Majlesi Journal of Electrical EngineeringThis paper presents a new method for optimal multi-objective reconfiguration of distribution system based on the novel Intelligent Water Drops (IWD) algorithm in order to mitigation of losses, improving the voltage profile and equalizing the feeder load ...
Hajar Bagheri Tolabi, Mohd Hasan Ali
doaj
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Engineering ReportsInsufficient reactive power in electrical power systems leads to voltage instability, limiting the ability to deliver power to loads and adversely affecting overall system reliability.
Abere Takele Alemu +1 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source