Results 111 to 120 of about 5,133,988 (300)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

AI-Enhanced Wide Supply Voltage Bandgap Voltage Reference Circuit With Multi-Objective Optimization for Automotive Applications

open access: yesIEEE Open Journal of Circuits and Systems
This paper presents a bandgap voltage reference (BGR) circuit with a wide supply voltage and temperature range, suitable for automotive applications.
U Chi-Wa   +4 more
doaj   +1 more source

Design of a low noise multistage voltage reference

open access: yes, 2005
This report presents a design of a low noise multistage voltage reference based on current-mode, which generates ± 200mV reference voltage. The reference circuit was designed under AMIS 0.5um process and typical supply voltage 1.2V.
Rita Munarwi.
core  

A DC Voltage Reference Based on MEMS

open access: yes, 2004
A micromechanical moving plate capacitor has been designed and fabricated for use as the key component in a DC voltage reference. The reference is based on the characteristic pull-in property of a capacitive MEMS device.
J. Kyynarainen   +13 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Investigation into voltage and process variation-aware manufacturing test

open access: yes, 2009
Increasing integration and complexity in IC design provides challenges for manufacturing testing. This thesis studies how process and supply voltage variation influence defect behaviour to determine the impact on manufacturing test cost and quality.
Ingelsson, Bo Urban
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Stable SOI micromachined electrostatic AC voltage reference

open access: yes, 2005
We have designed and manufactured a micromachined moving plate capacitor to be used as an AC voltage reference in electrical metrology. The reference is based on the characteristic AC current–voltage curve of the component having a maximum, the value of ...
Suhonen, Mika   +7 more
core   +1 more source

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