Results 201 to 210 of about 5,133,988 (300)

Hybrid TSA-TLBO optimization of an EF₂ resonant DC-DC converter for energy-efficient fuel cell electric vehicles with reduced battery dependency. [PDF]

Sci Rep
Manuel Raj JM, Vennapusa MKR, Subramani S, Devarajan G.   +3 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

A low-cost modular PCB assembly for functional and in-circuit testing. [PDF]

HardwareX
Puentes-Conde GM, Sifuentes E, Molina J, Enríquez-Aguilera F, Bravo G, Ávila AH.   +5 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Correlated Noise Reduction in a CMOS ECG Amplifier: Opportunities and Limitations. [PDF]

Sensors (Basel)
Olivieri R, Tatangelo G, Khanehbeygi M, Barile G, Pantoli L, Stornelli V, Ferri G.   +6 more
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Flexible h-BN/GaN Heterostructure Thin-Film Piezoelectric Sensors for Harsh Environments. [PDF]

Materials (Basel)
Peng Y, Wei W, Hu Z, Huang X, Bai J, Xie X, He Q, Zhou Y, Huang B, Zhang Z, Ding L, Zhong Q, Liu L.   +12 more
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Seamless grid following and grid forming inverter mode transition enabled by machine-learning based SCR estimation and smooth switching control. [PDF]

Sci Rep
Rajamallaiah A, Guerrero JM, Pavankumar Y, Bingi K, Yousaf MZ, Alghaythi ML, Alshammari MS.   +6 more
europepmc   +1 more source