Results 51 to 60 of about 47,285 (266)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Experimental validation of a low‐voltage regulator model—A case study of a Maltese low‐voltage feeder

IET Renewable Power Generation
Solar photovoltaics in Malta have increased substantially over the years, both at large scale and residential scale. The present installed capacity is already having a negative impact on Malta's’ grid infrastructure, causing problems due to the reverse ...
John Licari, Cyril Spiteri Staines, Alexander Micallef, Stefan Hoppert   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Optimized Phase‐shift Tuning via Equivalent Small Parameter Modeling for Ripple Reduction in Asymmetric Parallel Multi‐Module DC‐DC Converters

IET Power Electronics
In photovoltaic power generation applications, multiple low‐voltage PV modules must be boosted and connected in parallel for high power output. However, due to the variability of PV energy input, the parallel DC‐DC converter modules often operate under ...
Xiuyun Zhang, Guidong Zhang, Samson S. Yu, Zhenyu Yi   +3 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Rational distribution of excess regenerative energy in electric transport systems on the basis of fuzzy logic application [PDF]

Archives of Transport, 2017
Purpose. To develop the fuzzy model of distribution of excess regenerative energy in traction and external power supply systems allowing to exercise effective operation of the power equipment. Relevance.
Oleg Sablin, Valeriy Kuznetsov, Victor Shinkarenko, Alexander Ivanov   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Accurate voltage regulation for a DC microgrid using nonlinear state feedback controller

IET Generation, Transmission & Distribution
The high penetration of distributed generation systems poses challenges in effectively managing both DC bus voltage and power‐sharing in DC microgrids (MGs).
Mohammadreza Arabshahi, Younes Saeidinia, Hossein Torkaman   +2 more
doaj   +1 more source

Voltage-Gated Potassium Channels as Regulators of Cell Death

Frontiers in Cell and Developmental Biology, 2020
Ion channels allow the flux of specific ions across biological membranes, thereby determining ion homeostasis within the cells. Voltage-gated potassium-selective ion channels crucially contribute to the setting of the plasma membrane potential, to volume
Magdalena Bachmann, Magdalena Bachmann, Weiwei Li, Michael J. Edwards, Syed A. Ahmad, Sameer Patel, Ildiko Szabo, Ildiko Szabo, Erich Gulbins, Erich Gulbins   +9 more
doaj   +1 more source