Results 231 to 240 of about 1,906,569 (335)

Development of a Lo Ra-based multi-node wireless sensor network for real-time vibration and tilt monitoring of high-voltage transmission line towers using MEMS accelerometers [PDF]

Suthichai Wattanapruk
openalex   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Cholesterol modulates the structural dynamics of the paddle motif loop of KvAP voltage sensor. [PDF]

Curr Res Struct Biol
Das A, Bysack A, Raghuraman H.
europepmc   +1 more source

Voltage-to-frequency converter with digital self-calibration using on-chip ring oscillator reference for radiation-tolerant sensor interfaces [PDF]

Henrique Ornelas, Filomena Osório, Gaspar Outeiro   +2 more
openalex   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Different fluorescent labels report distinct components of spHCN channel voltage sensor movement. [PDF]

J Gen Physiol
Wojciechowski MN, McKenzie CE, Hung A, Kuanyshbek A, Soh MS, Reid CA, Forster IC.   +6 more
europepmc   +1 more source

Ambient RF energy harvesting using voltage doubler rectifier for battery-free agricultural sensor networks: Design, statistical analysis, and machine learning validation

Md. Atik Hasan Nishat, Prithwiraj Biswas Pallab, Nowrin Jannat, Saleha Nasrin Mishu, Md. Fahad Ullah Utsho, Md. Bipul Islam, Riaz Uddin Mondal, Md. Firoz Ahmed, M. Hasnat Kabir   +8 more
openalex   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Mechanical Fault Diagnosis of High-Voltage Circuit Breakers Based on Multi-Sensor Gramian Angular Field and Deep Residual Network

Xining Li, Hanyan Xiao, Ke Zhao, Lei Sun, Tianxin Zhuang, Haoyan Zhang, Hongwei Mei   +6 more
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PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source