Results 101 to 110 of about 261,450 (281)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Energy Science & EngineeringThe increased demand for electricity has forced power systems to operate near their stability limits. Optimal reactive power planning (ORPP) can enhance voltage stability and provide much‐needed support for grid operation. Flexible AC transmission system
Rawan Abu Zeitawyeh, Ayman Faza
doaj +1 more source
New Performance Indices for Voltage Stability Analysis in a Power System
Energies, 2017 The frequent occurrence of voltage instability in a modern power system is alarming and thus, has been of great concern to power system utilities. In this paper, a new performance index based on the power flow solutions for voltage stability assessment ...
Isaiah Adebayo, Yanxia Sun
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Ain Shams Engineering Journal, 2014 This paper presents the application of Multi-Objective Genetic Algorithm to solve the Voltage Stability Constrained Optimal Power Flow (VSCOPF) problem.
J. Preetha Roselyn +2 more
doaj +1 more source
2010 Conference Proceedings IPEC, 2010 Abstract: Voltage instability is a major threat for security of power systems. Preserving voltage security margin at a certain limit is a vital requirement for today’s power systems. Assessment of voltage security margin is a challenging task demanding sophisticated indices.
M. R. Aghamohammadi +2 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Zhongguo dianliThe ultra high voltage direct current (UHVDC) transmission system based on line commutation converters (LCCs) is the main technical means for long-distance and high-capacity transmission.
Shuyi SHEN +5 more
doaj +1 more source