Results 91 to 100 of about 565,077 (289)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Irreversibility of Electrical Insulating Material Properties

Advances in Electrical and Electronic Engineering, 2007
Property changes in electrical insulating materials that appear during repeated voltage stress (e. g. in an applied voltage test) are an often discussed problem. The voltage exposure leads to irreversible changes in a negative sense as this investigation
Vaclav Mentlik, Radek Polansky
doaj  

Solution to reduce voltage stress of sub-module in LCC–MMC transmission system at the condition of communication fault

The Journal of Engineering, 2018
Line commutate converter–modular multilevel converter (LCC–MMC) hybrid high voltage direct current (HVDC) system combines the advantages of both LCC-HVDC and MMC-HVDC, and will be wildly used in the future.
Dengjiang Xing, Jianjun Su, Dingwen Hu, Shumin Sun, Yan Chen, Xianwei Wang, Jun Zhang, Weizheng Yao, Jinlong Wu   +8 more
doaj   +1 more source

Role of Self-Assembled Monolayers on Improved Electrical Stability of Amorphous In-Ga-Zn-O Thin-Film Transistors

, 2014
Self-assembled monolayers (SAMs) have been used to improve both the positive and negative bias-stress stability of amorphous indium gallium zinc oxide (IGZO) bottom gate thin film transistors (TFTs).
Bluhm, Hendrik, Du, Xiaosong, Flynn, Brendan T., Herman, Gregory S., Motley, Joshua R., Stickle, William F.   +5 more
core   +1 more source

Hydrogen sulphide regulates inward-rectifying K+ channels in conjunction with stomatal closure [PDF]

, 2015
Hydrogen sulphide (H2S) is the third biological gasotransmitter and, in animals, affects many physiological processes by modulating ion channels. H2S has been reported to protect plants from oxidative stress in diverse physiological responses. H2S closes
Blatt, Mike R., Garia-Mata, Carlos, Papanatsiou, Maria, Scuffi, Denisse   +3 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Stress waves in an isotropic elastic plate excited by a circular transducer [PDF]

Steady state harmonic stress waves in an isotropic elastic plate excited on one face by a circular transducer are analyzed theoretically. The transmitting transducer transforms an electrical voltage into a uniform normal stress at the top of the plate ...
Karagulle, H., Lee, S. S., Williams, J. H., Jr.   +2 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source