Results 141 to 150 of about 229,601 (311)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Conversor flyback modular conectado em série na entrada e série na saída operando no modo descontínuo com pulso único de comando [PDF]

open access: yes, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2014Este trabalho apresenta uma nova estrutura de conversor CC-CC unidirecional, modular, adequado às ...
Faust, Rafael Gomes
core  

A Single Source Quadruple Boost Nine-Level Switched-Capacitor Inverter With Reduced Components and Continuous Input Current

open access: yesIEEE Access
The multilevel inverter (MLI) serves as a pivotal class of power electronic converters, well-suited for high-power applications at medium voltage levels, ensuring superior power quality.
Devanand Kumar   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Hybrid-Oxide Two-Stacked-FET CMOS Power Amplifier With Optimized Gate Impedance for X-Band Applications

open access: yesIEEE Access
This paper presents a hybrid-oxide (HO) stacked-FET architecture aimed at enhancing the output power of high-frequency CMOS power amplifiers. In the proposed topology, a thin-gate-oxide transistor is employed as the common-source (CS) device, while a ...
Joonseok Park   +3 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Modeling and Experimental Verification of a Single-Switch Quadratic Boost DC–DC Converter with High Voltage Gain for Energy Harvesting

open access: yesEnergies
This paper presents an enhanced non-isolated single-switch quadratic boost DC-DC converter. The proposed topology employs a single active switch, two inductors, two capacitors, and three diodes.
Niloufar Dizangian   +2 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

The Influence of Material Modification and Residues on Space Charge Accumulation in XLPE for DC Power Cable Application [PDF]

open access: yes, 2007
The effects of material modification and cross-linking by-products (residues) quantity on space charge accumulation and decay in XLPE have been investigated using the pulsed electro-acoustic technique.
Fothergill, J C   +3 more
core  

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