Results 111 to 120 of about 1,151,601 (306)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Self-driven oscillation in Coulomb blockaded suspended carbon nanotubes

, 2020
Suspended carbon nanotubes are known to support self-driven oscillations due to electromechanical feedback under certain conditions, including low temperatures and high mechanical quality factors.
Baugh, Jonathan, Willick, Kyle
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Self-Duality in Superconductor-Insulator Quantum Phase Transitions

, 2000
It is argued that close to a Coulomb interacting quantum critical point, the interaction between two vortices in a disordered superconducting thin film separated by a distance $r$ changes from logarithmic in the mean-field region to $1/r$ in the region ...
A. F. Hebard, A. K. Nguyen, A. M. J. Schakel, A. M. J. Schakel, A. M. J. Schakel, A. M. J. Schakel, A. M. J. Schakel, A. Yazdani, D. S. Fisher, D. Shahar, H. Kleinert, H. P. Wei, H. S. J. van der Zant, I. F. Herbut, J. Hove, J. Pearl, M. Greiter, M. Kiometzis, M. Kiometzis, M. P. A. Fisher, M. P. A. Fisher, M. Peskin, M. R. Beasley, N. Goldenfeld, P. G. de Gennes, P. Olsson, P. R. Thomas, S. L. Sondhi, S. M. Girvin, S. V. Kravchenko, X. G. Wen   +30 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Research on the Strategy of Photovoltaic Grid-connected Generation and Reactive Power Regulation

Kongzhi Yu Xinxi Jishu, 2013
It designed a photovoltaic (PV) grid-connected power conditioner system integrating grid-connected generation and reactive power regulation , in which the PV grid-connected inverter can provide active power for grid and output reactive power which the ...
ZHAO Xianggui, WU Hengliang, CHEN Yifeng, WANG Nan   +3 more
doaj  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Probing the charge of a quantum dot with a nanomechanical resonator

, 2012
We have used the mechanical motion of a carbon nanotube (CNT) as a probe of the average charge on a quantum dot. Variations of the resonance frequency and the quality factor are determined by the change in average charge on the quantum dot during a ...
A. Taspinar, B. H. Schneider, G. A. Steele, G. Labadze, H. B. Meerwaldt, H. B. Meerwaldt, H. S. J. van der Zant, R. Lifshitz, Ya. M. Blanter   +8 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source