Results 41 to 50 of about 1,341 (259)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Performance of a Three-Phase Induction Motor under and over Unbalance Voltage

open access: yesTikrit Journal of Engineering Sciences, 2022
Voltage unbalance is an adverse global phenomenon impacting three-phase induction motor output. Three-phase source voltage may become imbalanced in a variety of respects, while a balanced system preserves stable voltage magnitude and angles in three ...
Abdulsatar H. Jassim   +2 more
doaj  

Fair Power Factor Billing Under Unbalanced and Nonsinusoidal Voltage Supply

open access: yesIEEE Access, 2022
Utilities apply an additional fee for medium and large customers with low power factors. However, unfair financial charges may occur in installations subjected to voltage unbalance and harmonic distortion.
Victor P. Brasil   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Optimal planning of uncertain renewable energy sources in unbalanced distribution systems by a multi‐objective hybrid PSO–SCO algorithm

open access: yesIET Renewable Power Generation, 2022
High penetration of Renewable Energy Sources into unbalanced distribution systems faces many challenges due to the uncertainty nature of both Renewable Energy Sources and loads as well as the unbalance degree of the distribution systems.
Eman S. Ali   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Assessing the Static Security of the Italian Grid by Means of the N-1 Three-Phase Contingency Analysis

open access: yesEnergies
The ongoing replacement of synchronous machine generators (SMs) with converter-interface generators (CIGs) is raising the voltage unbalance of power systems, affecting power quality and grid stability.
Giovanni Gardan   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

A novel islanding detection method for microgrid using complex voltage unbalance factor

open access: yesElectrical Engineering
Abstract Accurate islanding detection is vital for grid stability, power system reliability and for sustainable energy practices. To address this, the paper introduces a novel technique, the Complex Voltage Unbalance Factor which is the ratio of negative and positive sequence voltage at the rate of angle. The magnitude of this ratio and
SUDHEEKSHA MISRA, Bhola Jha, V. M Mishra
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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