Results 81 to 90 of about 720,604 (270)
A gut-to-brain signal of fluid osmolarity controls thirst satiation. [PDF]
, 2019 Satiation is the process by which eating and drinking reduce appetite. For thirst, oropharyngeal cues have a critical role in driving satiation by reporting to the brain the volume of fluid that has been ingested1-12.
Ahn, Jamie S +11 more
core +1 more source
Capillary focusing close to a topographic step: Shape and instability of confined liquid filaments
, 2014 Step-emulsification is a microfluidic technique for droplet generation which relies on the abrupt decrease of confinement of a liquid filament surrounded by a continuous phase.
Afkhami, S. +3 more
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
, 2019 The volume of fluid (VOF) method is a popular approach for multiphase flow modeling. The open-source computational fluid dynamics (CFD) software, OpenFOAM, implements a variety of VOF-based solvers and provides users a wide range of turbulence models ...
Anglart, Henryk, Fan, Wenyuan
core +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Investigating the in-/through-plane effective diffusivities of dry and partially-saturated gas diffusion layers [PDF]
, 2018 In this study, the effective oxygen diffusivity in the dry or partially-saturated gas diffusion layer (GDL) is numerically investigated by an oxygen diffusion model in GDLs reconstructed by a stochastic method.
Jiao, K, Niu, Z, Wang, Y, Wu, J
core
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Petroleum Exploration and DevelopmentAn optimization method of fracturing fluid volume strength was introduced taking well X-1 in Biyang Sag of Nanxiang Basin as an example. The characteristic curves of capillary pressure and relative permeability were obtained from history matching between
Tingxue JIANG +8 more
doaj +1 more source
Two-phase flow and oxygen transport in the perforated gas diffusion layer of proton exchange membrane fuel cell [PDF]
, 2019 Liquid water transport in perforated gas diffusion layers (GDLs)is numerically investigated using a three-dimensional (3D)two-phase volume of fluid (VOF)model and a stochastic reconstruction model of GDL microstructures.
Bao, Z +5 more
core
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source