Results 131 to 140 of about 8,018,700 (214)

Centenários : um modelo de longevidade

, 2016
Trabalho final de mestrado integrado em Medicina, área cientifica de Geriatria, apresentado á Faculdade de Medicina da Universidade de CoimbraA evolução da ciência e da tecnologia tem permitido o prolongamento da sobrevivência da espécie humana até ...
Côrro, Helena Sofia Fernandes Loureiro do
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Brazilian Guidelines of Hypertension - 2020. [PDF]

Arq Bras Cardiol, 2021
Barroso WKS, Rodrigues CIS, Bortolotto LA, Mota-Gomes MA, Brandão AA, Feitosa ADM, Machado CA, Poli-de-Figueiredo CE, Amodeo C, Mion Júnior D, Barbosa ECD, Nobre F, Guimarães ICB, Vilela-Martin JF, Yugar-Toledo JC, Magalhães MEC, Neves MFT, Jardim PCBV, Miranda RD, Póvoa RMDS, Fuchs SC, Alessi A, Lucena AJG, Avezum A, Sousa ALL, Pio-Abreu A, Sposito AC, Pierin AMG, Paiva AMG, Spinelli ACS, Nogueira ADR, Dinamarco N, Eibel B, Forjaz CLM, Zanini CRO, Souza CB, Souza DDSM, Nilson EAF, Costa EFA, Freitas EV, Duarte EDR, Muxfeldt ES, Lima Júnior E, Campana EMG, Cesarino EJ, Marques F, Argenta F, Consolim-Colombo FM, Baptista FS, Almeida FA, Borelli FAO, Fuchs FD, Plavnik FL, Salles GF, Feitosa GS, Silva GVD, Guerra GM, Moreno Júnior H, Finimundi HC, Back IC, Oliveira Filho JB, Gemelli JR, Mill JG, Ribeiro JM, Lotaif LAD, Costa LSD, Magalhães LBNC, Drager LF, Martin LC, Scala LCN, Almeida MQ, Gowdak MMG, Klein MRST, Malachias MVB, Kuschnir MCC, Pinheiro ME, Borba MHE, Moreira Filho O, Passarelli Júnior O, Coelho OR, Vitorino PVO, Vitorino PVO, Ribeiro Junior RM, Esporcatte R, Franco R, Pedrosa R, Mulinari RA, Paula RB, Okawa RTP, Rosa RF, Amaral SLD, Ferreira-Filho SR, Kaiser SE, Jardim TSV, Guimarães V, Koch VH, Oigman W, Nadruz W.   +97 more
europepmc   +1 more source

Parâmetros genéticos e ambientais na construção da longevidade de sementes de soja.

A longevidade da semente de soja é vital para enfrentar desafios logísticos e climáticos, sendo determinada pela interação Genótipo (G) x Ambiente (A). O estudo avaliou 26 cultivares em duas safras, medindo a longevidade pela redução de 50% da germinação
SILVA, E. A. A., KIEVITSBOSCH, C. P. C., HENNING, F. A., PERISSATO, S. M., CHAMMA, L.   +4 more
core  

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Commodity risk assessment of Ficus carica plants from Israel. [PDF]

EFSA J, 2021
EFSA Panel on Plant Health (PLH), Bragard C, Dehnen-Schmutz K, Di Serio F, Jacques MA, Jaques Miret JA, Justesen AF, MacLeod A, Magnusson CS, Milonas P, Navas-Cortes JA, Parnell S, Potting R, Reignault PL, Thulke HH, van der Werf W, Civera AV, Yuen J, Zappalà L, Battisti A, Mas H, Rigling D, Mosbach-Schulz O, Gonthier P.   +23 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Population-Based Health Survey in the municipality of São Paulo 2024: methodological and operational aspects. [PDF]

Rev Bras Epidemiol
Cesar CLG, Bassichetto KC, Silva ZPD, Louvison MCP, Fisberg RM, Alves MCGP, Escuder MML, Alencar GP, Bernal RTI, Santos EFS, Luiz ODC, Goldbaum M.   +11 more
europepmc   +1 more source

Facial thread lifting with suture suspension. [PDF]

Braz J Otorhinolaryngol, 2017
Tavares JP, Oliveira CACP, Torres RP, Bahmad F.   +3 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source