Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Corrigendum/Erratum to "Wastewater treatment in tropical, vertical up-flow constructed wetlands with selected macrophytes species: A preliminary analysis" [Heliyon Volume 11, Issue 1, 15 January 2025, e41207]. [PDF]
Geleto M, Ulsido MD, Berego YS.
europepmc +1 more source
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick +19 more
wiley +1 more source
Corrigendum to "Impact of montmorillonite reinforcement on the physical recyclability of biobased and petroleum-based polyesters" [Volume 11, Issue 6, 20 March 2025, e43022.DOI: 10.1016/j.heliyon.2025.e43022]. [PDF]
Taha ZT, Bata A, Molnár B, Ronkay F.
europepmc +1 more source
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Editorial - Volume 04, Número 11 (2017)
John A. Fossa +2 more
doaj +1 more source
Corrigendum to "Identification of climate-sensitive disease incidences in Vietnam: A longitudinal retrospective analysis of infectious disease rates between 2014 and 2022" [Heliyon Volume 11, Issue 2, January 30, 2025, Article e41902]. [PDF]
Hoang CQ +7 more
europepmc +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source

