Results 51 to 60 of about 3,416,127 (312)
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Dagstuhl Reports, Volume 11, Issue 5, May 2021, Complete Issue
Dagstuhl Reports, Volume 11, Issue 5, May 2021, Complete ...
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Dagstuhl Reports, Volume 9, Issue 11, November 2019, Complete Issue
Dagstuhl Reports, Volume 9, Issue 11, November 2019, Complete ...
core +1 more source
Dagstuhl Reports, Volume 11, Issue 10, November 2021, Complete Issue
Dagstuhl Reports, Volume 11, Issue 10, November 2021, Complete ...
core +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Dagstuhl Reports, Volume 6, Issue 11, November 2016, Complete Issue
Dagstuhl Reports, Volume 6, Issue 11, November 2016, Complete ...
core +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Dagstuhl Reports, Table of Contents, Volume 11, Issue 5, 2021
Dagstuhl Reports, Table of Contents, Volume 11, Issue 5 ...
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We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source

