Results 191 to 200 of about 71,898,511 (301)

Effect of Wall Motion Sampling on CFD-Derived Left Atrial Flow Metrics. [PDF]

Int J Numer Method Biomed Eng
Stöcker Y, Guerrero-Hurtado M, Durán E, Gonzalo A, Ristić Z, Telle Å, Kassar A, Haykal R, Akoum N, Boyle PM, Flores O, Augustin CM, Del Alamo JC, García-Villalba M.   +13 more
europepmc   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Numerical Simulation of Spatial Distribution Characteristics of Hazardous Gas Clouds from Leakage at a Hydrogen-Blended Natural Gas Distribution Station. [PDF]

ACS Omega
Wang D, Jin Z, Yu Q, Liang P.
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Dosimetric Outcomes of Definitive Radiation Therapy to Anal Squamous Cell Carcinoma in a Single Institution Using Volumetric Modulated Arc Therapy Evaluated Against Australian and International Treatment Planning Guidelines. [PDF]

J Med Radiat Sci
Alshamrani F, Hsieh M, Karl A, Chamberlain L, Greenham S, Goodworth J, Wood M, Shakespeare T, Le T, Tahir AM.   +9 more
europepmc   +1 more source

Reduced renal length and volume 20 years after very preterm birth. [PDF]

Pediatr Nephrol, 2010
Keijzer-Veen MG, Devos AS, Meradji M, Dekker FW, Nauta J, van der Heijden BJ.   +5 more
europepmc   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Effects of transient intravascular volume overload on endothelial glycocalyx thickness in healthy anesthetized cats. [PDF]

Front Vet Sci
Yozova ID, Thomson N, Irie M, Owen R, Munday JS.   +4 more
europepmc   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source