Results 41 to 50 of about 16,702,141 (260)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Dagstuhl Reports, Volume 4, Issue 9, September 2014, Complete Issue

, 2015
Dagstuhl Reports, Volume 4, Issue 9, September 2014, Complete ...

core   +1 more source

Dagstuhl Reports, Volume 9, Issue 7, July 2019, Complete Issue

, 2020
Dagstuhl Reports, Volume 9, Issue 7, July 2019, Complete ...

core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Dagstuhl Reports, Table of Contents, Volume 12, Issue 9, 2022

, 2023
Dagstuhl Reports, Table of Contents, Volume 12, Issue 9 ...

core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Volume 9 numéro 2

Captures
Si, ces dix dernières années, nos dossiers thématiques nous ont permis de faire la part belle aux images, le dossier « Portraits sonores de pays » ouvre les pages de la revue au traitement du son et exploite cette capacité citationnelle permise par notre
Bertrand Gervais
doaj   +1 more source

EDITORIAL VOLUME 9 ISSUE 1

Revista de Psicología y Ciencias del Comportamiento de la Unidad Académica de Ciencias Jurídicas y Sociales, 2018
Editorial Volume 9 Issue 1 (January-June, 2018)
Comité
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Dagstuhl Reports, Volume 12, Issue 9, September 2022, Complete Issue

, 2023
Dagstuhl Reports, Volume 12, Issue 9, September 2022, Complete ...

core   +1 more source