Results 91 to 100 of about 4,089,988 (286)

Thermal Conductivity Characteristics of Thermal Insulation Materials Immersed in Water for Cold-Region Tunnels

Advances in Materials Science and Engineering, 2020
This study investigates the distribution of pore water on the basis of the measured mass moisture content after soaking the tunnel insulation material. This study also analyzes the influence of the distribution of pore water on the thermal conductivity ...
Youyun Li, Yongmei Sun, Yuan Zhuang, LiMin Duan, Ke Xie   +4 more
doaj   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

A new type of automatic gas distribution system applied in flameproof test devices

Gong-kuang zidonghua, 2014
In view of problems of slow speed of gas distribution, big volume of system of traditional gas distribution methods applied in flameproof test devices, an automatic gas distribution system based on mass flow method was designed. The system uses mass flow
JI Xiaohua, WANG Zhiming
doaj   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Predicting Spatial Distribution of Stand Volume Using Geostatistics

Jurnal Manajemen Hutan Tropika, 2011
Pendugaan volume tegakan hutan alam biasanya dilakukan dengan metode penarikan contoh (sampling) non-spasial. Dalam penelitian ini, dikembangkan metode pendugaan spasial dengan pendekatan geostatistika yang diterapkan untuk menduga dan memetakan sebaran ...
Tatang Tiryana
doaj  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Distribution of the Volume of Weighted Gaussian Simplex

Journal of Mathematical Sciences, 2022
Let $X_0, \ldots, X_l$ be independent standard Gaussian vectors in $\mathbb{R}^d$ such that $l \leqslant d$. We derive an explicit formula for the distribution of the volume of weighted Gaussian simplex without the origin -- $l$-dimensional simplex $\mathrm{conv}( _0X_0, \ldots, _lX_l)$ ($ _0, \ldots, _l > 0$).
openaire   +2 more sources

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Experimental study on purification by pressure ventilation of coal mine refuge chamber

Gong-kuang zidonghua, 2015
Relationship formula between average concentration of harmful gas and pressure ventilation supply volume in refuge chamber was given, CO2 concentration distribution in refuge chamber under conditions of different pressure ventilation supply volume and ...
HE Tingmei
doaj   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source