Results 61 to 70 of about 5,814,761 (295)

A Review of Therapeutic Agents Given by Convection-Enhanced Delivery for Adult Glioblastoma

open access: yesPharmaceuticals
Glioblastoma remains a devastating disease with a bleak prognosis despite continued research and numerous clinical trials. Convection-enhanced delivery offers researchers and clinicians a platform to bypass the blood–brain barrier and administer drugs ...
Nathaniel W. Rolfe   +3 more
doaj   +1 more source

Radiologic-pathologic analysis of increased ethanol localization and ablative extent achieved by ethyl cellulose

open access: yesScientific Reports, 2021
Ethanol provides a rapid, low-cost ablative solution for liver tumors with a small technological footprint but suffers from uncontrolled diffusion in target tissue, limiting treatment precision and accuracy.
Erika Chelales   +6 more
doaj   +1 more source

The Phase Transition to Eternal Inflation

open access: yes, 2008
For slow-roll inflation we study the phase transition to the eternal regime. Starting from a finite inflationary volume, we consider the volume of the universe at reheating as order parameter.
Creminelli, Paolo   +4 more
core   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Applying linear and non-linear methods for parallel prediction of volume of distribution and fraction of unbound drug. [PDF]

open access: yesPLoS ONE, 2013
Volume of distribution and fraction unbound are two key parameters in pharmacokinetics. The fraction unbound describes the portion of free drug in plasma that may extravasate, while volume of distribution describes the tissue access and binding of a drug.
Eva M del Amo   +5 more
doaj   +1 more source

The optical characterisation of spray and soot formation in a diesel engine [PDF]

open access: yes, 2010
Laser sheet drop-sizing (LSD) measurements of a Diesel spray and simultaneous laser induced incandescence/Mie scattering measurements of soot have been performed in an optically accessible, common rail, 1.9 litre, turbo-charged, direct injection Diesel ...
Greenhalgh, D. A., Lockett, R. D.
core  

Isoperimetric-type inequalities for iterated Brownian motion in R^n

open access: yes, 2006
We extend generalized isoperimetric-type inequalities to iterated Brownian motion over several domains in $\RR{R}^{n}$. These kinds of inequalities imply in particular that for domains of finite volume, the exit distribution and moments of the first exit
Allouba   +15 more
core   +1 more source

Scaling Structures in Four-dimensional Simplicial Gravity [PDF]

open access: yes, 1996
Four-dimensional(4D) spacetime structures are investigated using the concept of the geodesic distance in the simplicial quantum gravity. On the analogy of the loop length distribution in 2D case, the scaling relations of the boundary volume distribution ...
Agishtein   +10 more
core   +2 more sources

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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