Results 111 to 120 of about 1,475,070 (295)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Aplication of Flotran CFD in ANSYS [PDF]
, 2014 Simulation program ANSYS. The aerodynamic simulation with CFD (Computational Fluid Dynamics). Finite element method (FEM). Volume element method (VEM).
Palko, Milan
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Simulation of Sloshing with the Volume of Fluid Method
Fluid Dynamics & Materials Processing, 2006 This paper opens a new horizon on the simulation of sloshing phenomena. One of the most popular Finite Volume methods called VOF (Volume Of Fluid) method is used for tracking the flow in containers. The algorithm is tested for different fluid elevations, physical conditions in different road curves and liquid properties.
M.H. Djavareshkian, M. Khalili
openaire +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Determination of gas volume trapped in a closed fluid system [PDF]
, 1971 Technique involves extracting known volume of fluid and measuring system before and after extraction, volume of entrapped gas is then computed. Formula derived from ideal gas laws is basis of this method.
Hunter, W. F., Jolley, J. E.
core +1 more source
DEVELOPMENT OF FINITE VOLUME METHODS FOR FLUID DYNAMICS
, 2007 Le but de cette thèse est de développer une méthode de volumes finis qui s'applique à une classe de maillages beaucoup plus grande que celle des méthodes classiques, limitées par des conditions d'orthogonalité très restrictives. On construit des opérateurs différentiels discrets agissant sur les trois maillages décalés nécessaires à la construction de ...
openaire +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Computational Modeling of Bubbles Growth Using the Coupled Level Set-Volume of Fluid Method. [PDF]
Eur J Mech B Fluids, 2020 Taqieddin A +3 more
europepmc +1 more source