Results 91 to 100 of about 8,298,416 (278)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Real-time external labeling layout algorithm for Direct Volume Rendering

open access: yesRevista Cubana de Informática Médica, 2016
Illustrations used in technical and scientific texts often employ labels to correlate the graphic elements and their textual descriptions. Researchers have proposed several algorithms to determine the layout of the annotations on images rendered at ...
Luis Guillermo Silva Rojas   +1 more
doaj   +2 more sources

Optimizing GPU Volume Rendering.

open access: yesJ. WSCG, 2006
Volume Rendering methods employing the GPU capabilities offer high performance on off-the-shelf hardware. In this article, we discuss the various bottlenecks found in the graphics hardware when performing GPU-based Volume Rendering. The specific properties of each bottleneck and the trade-offs between them are described.
Ruijters, Daniel, Vilanova, Anna
openaire   +3 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Reconstruction of gradient in volume rendering

open access: yesIEEE International Conference on Industrial Technology, 2003, 2004
This paper deals with reconstruction of the gradient in the volume element space that is required for shading in the volume rendering. The accuracy of the surface reconstruction in the volume rendering is very important task as well as reconstruction accuracy of the normal vector.
Mihajlović, Željka   +2 more
openaire   +2 more sources

Volume Rendering for High Dynamic Range Displays

open access: yes, 2005
Dynamic range restrictions of conventional displays limit the amount of detail that can be represented in volume rendering applications. However, high dynamic range displays with contrast ratios larger than 50;000 : 1 have recently been developed.
Ghosh, Abhijeet   +2 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Feature of Interest‐Based Direct Volume Rendering Using Contextual Saliency‐Driven Ray Profile Analysis

open access: yes, 2018
Direct volume rendering (DVR) visualization helps interpretation because it allows users to focus attention on the subset of volumetric data that is of most interest to them. The ideal visualization of the features of interest (FOIs) in a volume, however,
Fulham, M.   +4 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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