Results 61 to 70 of about 8,298,416 (278)

A Clustering Based Transfer Function for Volume Rendering Using Gray-Gradient Mode Histogram

IEEE Access, 2019
Volume rendering is an emerging technique widely used in the medical field to visualize human organs using tomography image slices. In volume rendering, sliced medical images are transformed into attributes, such as color and opacity through transfer ...
Yisha Lan, Yimin Ding, Xin Luo, Yanzhao Zhang, Chenxi Huang, E. Y. K. Ng, Weihong Huang, Xuezhong Zhou, Jie Su, Yonghong Peng, Zhicheng Wang, Yongqiang Cheng, Wenliang Che   +12 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance

Pediatric Blood &Cancer, EarlyView.
Dunia Hatabah, Martha E. Stewart, Nathan Maassel, James P. Stevens, Claudia R. Morris, Chris A. Rees   +5 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The Implementation of a WebGPU-Based Volume Rendering Framework for Interactive Visualization of Ocean Scalar Data

Applied Sciences
Visualization contributes to an in-depth understanding of ocean variables and phenomena, and a web-based three-dimensional visualization of ocean data has gained significant attention in oceanographic research.
Jiaqi Yu, Rufu Qin, Zhounan Xu
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Achieving Better Energy Efficiency in Volume Analysis and Direct Volume Rendering Descriptor Computation

Computers
Approaches aimed at achieving improved energy efficiency for determination of descriptors—used in volumetric data analysis and one common mode of scientific visualisation—in one x86-class setting are described and evaluated.
Jacob D. Hauenstein, Timothy S. Newman
doaj   +1 more source

Virtual Dissection: Emerging as the Gold Standard of Analyzing Living Heart Anatomy

Journal of Cardiovascular Development and Disease, 2020
Traditionally, gross cardiac anatomy has been described mainly based on the findings in the dissection suite. Analyses of heart specimens have contributed immensely towards building a fundamental knowledge of cardiac anatomy.
Justin T. Tretter, Saurabh Kumar Gupta, Yu Izawa, Tatsuya Nishii, Shumpei Mori   +4 more
doaj   +1 more source