Results 101 to 110 of about 23,199 (236)

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Semi‐Automatic Assessment of Crohn's Disease Activity by Combined Analysis of Bowel Lesions and Creeping Fat

Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 302-314, July 2026.
ABSTRACT Purpose To develop and evaluate Crohn‐BOOST, an open‐source tool enabling semi‐automatic segmentation of intestinal lesions and creeping fat on magnetic resonance enterography (MR Enterography), and to assess whether quantitative metrics derived from these segmentations relate to radiological disease activity scored with simplified MaRIA ...
Antoine Kneib, Astrée Lemore, Gabriela Hossu, Laurent Peyrin‐Biroulet, Valérie Laurent, Freddy Odille   +5 more
wiley   +1 more source

Dosimetric Comparison Using an Intraoral Stent during Volumetric-modulated Arc Therapy in a Patient with Carcinoma of the Tongue

Journal of Radiation and Cancer Research
A 47-year-old man diagnosed with carcinoma of the tongue and postsurgery was planned for adjuvant radiotherapy. He was simulated for radiotherapy with or without an acrylic intraoral stent (IOS). Two different radiotherapy treatment plans with volumetric-
Puja R. Londhe, Prasad Tanawade, Parag Watve, Yogesh Anap, Aditi Saha, Jaahid Mulani   +5 more
doaj   +1 more source

Pancreas, Muscle, and Subcutaneous Fat Atrophy in Patients Undergoing Radiation for Neuroblastoma

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
ABSTRACT Background/Objectives Radiation therapy (RT) is part of standard‐of‐care therapy in high‐risk neuroblastoma (HR‐NBL) but can significantly affect nearby tissue. The objectives of this study were (1) to characterize changes in pancreas volume after RT and (2) to characterize changes in body composition, including body weight percentile ...
Pradipta Debnath, Marissa Ray, Luke Pater, Alexandra O. Glenn, Stephen Hartman, Elanchezhian Somasundaram, Todd Jenkins, Juan P. Gurria, Katherine Somers, Andrew T. Trout, Meera Kotagal   +10 more
wiley   +1 more source

Image guided high-dose-rate brachytherapy versus volumetric modulated arc therapy for head and neck cancer: A comparative analysis of dosimetry for target volume and organs at risk

Radiology and Oncology, 2018
The aim of the study was to present dosimetric comparison of image guided high-dose-rate brachytherapy (IGBT) with volumetric modulated arc therapy (VMAT) for head and neck cancer regarding conformity of dose distribution to planning target volume (PTV ...
Akiyama Hironori, Pesznyák Csilla, Béla Dalma, Ferenczi Örs, Major Tibor, Polgár Csaba, Takácsi-Nagy Zoltán   +6 more
doaj   +1 more source

A Feasibility Study of the Repurposing of Prazosin to Improve Treatment Outcomes in Men Receiving Radiotherapy for Prostate Cancer (MiniRaP‐00)

The Prostate, Volume 86, Issue 8, Page 891-899, June 2026.
ABSTRACT Background Further work is needed to improve treatment outcomes for prostate cancer (PCa), with the repurposing of the α1‐adrenoreceptor antagonists presenting a potential solution. This feasibility clinical trial presents the first prospective data of the use of an α1‐adrenoreceptor antagonist in men undergoing radiotherapy for PCa.
Liam D. King, David Christie, Daniel Cehic, Wendy Dare, Russ Chess‐Williams, Donna Sellers, Catherine McDermott, Alexandra McCarthy, Shailendra Anoopkumar‐Dukie   +8 more
wiley   +1 more source

Comparative evaluation of two dose-volume histogram prediction tools for treatment planning: Treatment planning quality and dose verification accuracy

Technical Innovations & Patient Support in Radiation Oncology
Purpose: This study aims to compare treatment plans created using RapidPlan and PlanIQ for twelve patients with prostate cancer, focusing on dose uniformity, dose reduction to organs at risk (OARs), plan complexity, and dose verification accuracy.
Shoma Nakano, Motoharu Sasaki, Yuji Nakaguchi, Takeshi Kamomae, Kanako Sakuragawa, Yuto Yamaji, Hitoshi Ikushima   +6 more
doaj   +1 more source

Application of volumetric modulated arc therapy (VMAT) in a dual-vendor environment

Radiation Oncology, 2010
Background and Purpose The purpose of this study was to assess plan quality and treatment time achievable with the new VMAT optimization tool implemented in the treatment planning system Oncentra MasterPlan® as compared to IMRT for Elekta SynergyS ...
Weidner Karin, Dobler Barbara, Koelbl Oliver   +2 more
doaj   +1 more source

Converting Treatment Plans From Helical Tomotherapy to L-Shape Linac: Clinical Workflow and Dosimetric Evaluation. [PDF]

, 2018
This work evaluated a commercial fallback planning workflow designed to provide cross-platform treatment planning and delivery. A total of 27 helical tomotherapy intensity-modulated radiotherapy plans covering 4 anatomical sites were selected, including ...
Benedict, Stanley H, Fragoso, Ruben C, Nair, Chithra Kumaran, Qiu, Jianfeng, Rao, Shyam, Rong, Yi, Valicenti, Richard K, Wright, Cari, Yuan, Zilong   +8 more
core   +1 more source

Impact of Intraprostatic Simultaneous Integrated Boost on Long‐Term Outcomes in Unfavorable Intermediate‐Risk Prostate Cancer Treated With Dose‐Escalated Radiotherapy and Short‐Term Androgen Deprivation Therapy

The Prostate, Volume 86, Issue 8, Page 961-969, June 2026.
ABSTRACT Background Unfavorable intermediate‐risk prostate cancer (UIR‐PCa) represents a biologically heterogeneous subgroup with a higher risk of recurrence compared with favorable intermediate‐risk disease. Contemporary management frequently includes dose‐escalated radiotherapy (RT) combined with short‐term androgen deprivation therapy (ADT). Whether
Cem Onal, Aysenur Elmali, Birhan Demirhan, Ertugrul Senturk, Petek Erpolat, Ozan Cem Guler   +5 more
wiley   +1 more source