Results 221 to 230 of about 789,882 (292)

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

open access: yesAdvanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong   +15 more
wiley   +1 more source

Omnidirectional Interaction Networks Modulating Phenotypic Plasticity in the Gut Microbiota Towards Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
This study employs a spouse‐pair cohort design and an idopNetwork model that integrates evolutionary game theory, predator‐prey dynamics, and developmental modularity theory to reconstruct maximally informative microbial interaction networks. This approach reveals how interspecies interactions drive the phenotypic plasticity of the gut microbiota in ...
Huizhen Li   +15 more
wiley   +1 more source

Overlap Between Mandatory and Voluntary Value-Based Kidney Care Model Participation and Home Dialysis Use.

open access: yesJAMA Health Forum
Tummalapalli SL   +5 more
europepmc   +1 more source

Robust, Breathable and Stretchable Liquid Metal Composite Nanofibre for Physiological Electrical Signal Monitoring

open access: yesAdvanced Science, EarlyView.
A conductive TPU/liquid‐metal nanofibrous film is fabricated via ultrasonic dispersion, electrospinning, and mold imprinting. The film is breathable, stretchable, deformation‐stable, and provides electromagnetic shielding. n‐Butanol encapsulation mitigates liquid‐metal surface tension and improves biocompatibility. Stable ECG, EOG, EEG, and EMG signals
Cong Huang   +7 more
wiley   +1 more source

The Relationship Between Voluntary Rapid Blinking Rate and Future Development of Neurodegenerative Disease. [PDF]

open access: yesGeriatr Gerontol Int
Bahsi R   +9 more
europepmc   +1 more source

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