Results 71 to 80 of about 3,395 (297)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Heat distribution study on turbocharger turbine volute [PDF]
, 2012 The aimed of this project is to evaluate turbine’s performance based on its actual condition. Holset H3B nozzles turbine geometry was used as simulation model.
Ardani, Mohd. Ibthisham
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Diagnosis of Centrifugal Pump Faults Using Vibration Methods
, 2012 Pumps are the largest single consumer of power in industry. This means that faulty pumps cause a high rate of energy loss with associated performance degradation, high vibration levels and significant noise radiation.
Gu, Fengshou +6 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
, 2007 W pracy przedstawiono podstawowe wiadomości na temat taśmowych sprężyn paraboloidalnych oraz przykłady zastosowania ich w technice. Opisano aplikację internetową do projektowania taśmowych sprężyn paraboloidalnych, umożliwiającą obliczenie ich parametrów
Sileikis, W.
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Effects of cut volute profile on squirrel cage fan performance and flow field
Advances in Mechanical Engineering, 2018 The flow pattern in the volute of a squirrel cage fan is complicated and non-axisymmetric. In this article, the original volute profile of a squirrel cage fan was cut to control and reshape this non-axisymmetric flow structure.
Boyan Jiang, Hui Liu, Bin Li, Jun Wang
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Records of the Australian Museum, 1902 (Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Influence of different volute casings theoretical methods design on pump working processes
, 2021 The work is devoted to determining the influence of methods and recommendations for the design of a volute casing on the flow structure and the efficiency of the double-entry centrifugal pump.
Moloshnyi, Oleksandr Mykolaiovych +8 more
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