Results 21 to 30 of about 59,748 (259)

Potential value of triple drug therapy with ivermectin, diethylcarbamazine, and albendazole (IDA) to accelerate elimination of lymphatic filariasis and onchocerciasis in Africa [PDF]

open access: yes, 2017
Novel drugs are required for the elimination of infections caused by filarial worms, as most commonly used drugs largely target the microfilariae or first stage larvae of these infections.
Fischer, Peter U   +3 more
core   +6 more sources

The macrofilaricidal efficacy of repeated doses of ivermectin for the treatment of river blindness [PDF]

open access: yes, 2017
Background: Mass drug administration (MDA) with ivermectin is the cornerstone of efforts to eliminate human onchocerciasis by 2020 or 2025. The feasibility of elimination crucially depends on the effects of multiple ivermectin doses on Onchocerca ...
Basáñez, Maria-Gloria   +12 more
core   +2 more sources

The therapeutic efficacy and macrofilaricidal activity of doxycycline for the treatment of river blindness [PDF]

open access: yes, 2014
Background. Onchocerca volvulus and lymphatic filariae, causing river blindness and elephantiasis, depend on endosymbiotic Wolbachia bacteria for growth, development, fertility, and survival.
Achim Hoerauf   +43 more
core   +1 more source

Gallbladder Volvulus [PDF]

open access: yesHPB Surgery, 1992
A case of torsion of the gallbladder is presented. This is a rare condition that occurs more frequently in elderly females, it is associated with anatomical variants related to abnormal fixation of the gallbladder to the liver bed. It is usually diagnosed at laparotomy and treatment consists of cholecystectomy.
Gonzalez-Fisher, Ricardo F.   +3 more
openaire   +2 more sources

Phylogenetic relationships of the Wolbachia of nematodes and arthropods [PDF]

open access: yes, 2006
Wolbachia are well known as bacterial symbionts of arthropods, where they are reproductive parasites, but have also been described from nematode hosts, where the symbiotic interaction has features of mutualism.
Claire Conlon   +7 more
core   +3 more sources

Stage-specific proteomes from onchocerca ochengi, sister species of the human river blindness parasite, uncover adaptations to a nodular lifestyle [PDF]

open access: yes, 2016
Despite 40 years of control efforts, onchocerciasis (river blindness) remains one of the most important neglected tropical diseases, with 17 million people affected.
Adam   +155 more
core   +5 more sources

Evidence of suppression of onchocerciasis transmission in the Venezuelan Amazonian focus. [PDF]

open access: yes, 2016
BACKGROUND: The World Health Organization (WHO) has set goals for onchocerciasis elimination in Latin America by 2015. Most of the six previously endemic countries are attaining this goal by implementing twice a year (and in some foci, quarterly) mass ...
Basanez, MG   +20 more
core   +2 more sources

VOLVULUS OF THE OMENTUM. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1904
Including my case nine instances of volvulus of the omentum have been recorded in surgical literature. These are as follows: Case 1. —Male, aged 35 years, a patient of Dr. Alfred Allman, for whom I operated. His mother, a sister and six children are living and in good health. He had never suffered from any serious illness. Four days before operation,
openaire   +2 more sources

Modelling the elimination of river blindness using long-term epidemiological and programmatic data from Mali and Senegal [PDF]

open access: yes, 2017
The onchocerciasis transmission models EPIONCHO and ONCHOSIM have been independently developed and used to explore the feasibility of eliminating onchocerciasis from Africa with mass (annual or biannual) distribution of ivermectin within the timeframes ...
Basáñez, M-G   +7 more
core   +6 more sources

The Wolbachia Genome of Brugia malayi: Endosymbiont Evolution within a Human Pathogenic Nematode [PDF]

open access: yes, 2005
Complete genome DNA sequence and analysis is presented for Wolbachia, the obligate alpha-proteobacterial endosymbiont required for fertility and survival of the human filarial parasitic nematode Brugia malayi. Although, quantitatively, the genome is even
  +204 more
core   +3 more sources

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