Results 101 to 110 of about 535,323 (308)

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić   +4 more
wiley   +1 more source

Cyclic vomiting syndrome: diagnostic approach and current management strategies

open access: yes, 2018
William J Hayes,1 Deidra VanGilder,2 Joseph Berendse,3 Michael D Lemon,3 John A Kappes4 1Department of Pharmacy Practice, South Dakota State University, Regional Health Medical Clinic, Rapid City, SD, USA; 2South Dakota State University, College of ...
VanGilder D   +4 more
core  

A scoping review of thresholds for responder and time‐to‐event analysis of patient‐reported outcomes in breast cancer trials

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Patient‐reported outcomes (PROs) are essential for assessing clinical benefit and tolerability from the patient's perspective. In oncology trials, PRO data analysis often involves responder and time‐to‐event analyses, which depend on predefined thresholds to determine clinically meaningful change.
Anna Margarete Maria Thurner   +5 more
wiley   +1 more source

The incidences of nausea and vomiting after general anesthesia with remimazolam versus sevoflurane: a prospective randomized controlled trial [PDF]

open access: yesKorean Journal of Anesthesiology
Background Postoperative nausea and vomiting (PONV) refers to nausea and vomiting that occurs within 24-h after surgery or in the post-anesthesia care unit (PACU).
Yeong Min Yoo   +4 more
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić   +7 more
wiley   +1 more source

Optimal management of severe nausea and vomiting in migraine: improving patient outcomes

open access: yes, 2013
Miguel JA Láinez,1,2 Ana García-Casado,1 Francisco Gascón11Servicio de Neurología, Hospital Clínico Universitario, Valencia, Spain; 2Departamento de Neurología, Universidad Católica de Valencia, Valencia ...
García-Casado A   +2 more
core  

Identificação de fatores de risco para náuseas e vômitos pós-operatórios. [PDF]

open access: yes, 2001
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Cirúrgica, Curso de Medicina, Florianópolis ...
Mottana, Lilian Viscara
core  

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden   +3 more
wiley   +1 more source

Chemotherapy-induced nausea and vomiting: exploring patients’ subjective experience

open access: yes, 2016
Noor Salihah,1 Nik Mazlan,2 Pei Lin Lua3 1Faculty of Health Sciences, Universiti Sultan Zainal Abidin, Kampus Gong Badak, Terengganu, 2Kulliyyah of Allied Health Sciences, International Islamic University Malaysia, Pahang, 3Community Health Research
Mazlan N, Salihah N, Lua PL
core  

The Case of Bezoar in a Patient Presenting with Vomiting

open access: yes, 2014
Bezoars are solid mass of a indigestible material accumulating in the gastrointestinal tract. Although rarely, bezoars may cause gastrointestinal obstruction. We aimed to present the case of a patient presenting with the complaint of vomiting in whom a
Hüsnü Aydın   +4 more
core   +1 more source

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