Results 191 to 200 of about 728,389 (310)

Novel antiemetic effect of naldemedine in patients initiating opioids for cancer pain: a secondary analysis of a randomized clinical trial. [PDF]

Oncologist
Higashibata T, Kessoku T, Kajiura S, Hirakawa M, Oyamada S, Ariyoshi K, Yamada T, Yamamoto Y, Moriwaki T, Nagaoka H, Takashima Y, Doki K, Mathis BJ, Tanaka K, Fuyuki A, Nakajima A, Ishihara Y, Hayashi R, Ando T, Kobayashi Y, Izawa N, Horie Y, Morita T, Hamano J.   +23 more
europepmc   +1 more source

A phase 3, randomized clinical trial of soticlestat as adjunctive therapy for Lennox–Gastaut syndrome

Epilepsia, EarlyView.
Soticlestat as adjunctive therapy for Lennox–Gastaut syndrome. Abstract Objective There remains a need for new treatments for Lennox–Gastaut syndrome (LGS), a developmental and epileptic encephalopathy with a heterogenous patient population that often requires polytherapy. The phase 3, randomized SKYWAY study (NCT04938427) investigated the efficacy and
Renzo Guerrini, Eric D. Marsh, Wei‐Ping Liao, Katsumi Imai, Ruzica Kravljanac, Anna Altmann, Cecil D. Hahn, Stéphane Auvin, Jimmy Schiemann, Yasir Khan, Pranab Mitra, Sarah I. Sheikh, Philipp von Rosenstiel, Mahnaz Asgharnejad, Dennis Dlugos, Venkatesha Murthy   +15 more
wiley   +1 more source

Megestrol acetate versus dexamethasone to prevent nausea and vomiting in patients with gastric or gastro-oesophageal junction cancer treated with oxaliplatin-based chemotherapy: study protocol of a multicentre, randomised, non-inferiority trial. [PDF]

BMJ Open
Luo H, Hu Q, Zeng L, Huang Q, Luo Y, Li T, Chen P, Yi C, Gou H.   +8 more
europepmc   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Benefits and risks of prophylactic glucocorticoids in platinum chemotherapy for extensive-stage small-cell lung cancer: A retrospective study. [PDF]

Mol Clin Oncol
Qingling W, Dafeng W, Yan Z, Xuebo Y.
europepmc   +1 more source

Epilepsy syndromes classification

Epilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell, Nicola Specchio, Rima Nabbout, Phillip L. Pearl, Kate Riney   +4 more
wiley   +1 more source

A Population-Based Survey on the Prevalence of Postoperative Nausea and Vomiting in the Qassim Region. [PDF]

Cureus
Almadhi MM, Aboelseoud MM, AlGharras AK, Almadud AA, Mohamed EA, Alshehri IM, Geddawy RM, AlGharras WK.   +7 more
europepmc   +1 more source

Symptom Clusters. [PDF]

, 2016
Barsevick, Andrea M.
core   +2 more sources

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Orthognathic surgery and postoperative nausea and vomiting: An 11-year retrospective observational study. [PDF]

PLoS One
Watanabe T, Uozumi R, Kawamura T, Sasaki M, Okada R, Inoue S, Kashiwagi M, Fukuhara S, Yamanaka S, Mishima S, Yamaguchi A, Hirota M.   +11 more
europepmc   +1 more source