Results 221 to 230 of about 546,786 (263)

Longitudinal associations between sleepiness and sleep disturbances across pregnancy

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Although sleep disturbances increase during pregnancy, sleepiness does not appear to follow a similar trajectory. Given that the relationship between sleep disturbances and sleepiness during pregnancy is understudied, we examined their associations to determine whether these relationships strengthen with advancing gestation.
Linda Aukia   +5 more
wiley   +1 more source

Tofacitinib Regulates β‐Catenin Nuclear Translocation to Inhibit FLS Migration and Alleviate Clinical Symptoms of RA

open access: yesiNew Medicine, EarlyView.
ABSTRACT Objective Tofacitinib is a Janus kinase (JAK) inhibitor approved for the treatment of moderate‐to‐severe rheumatoid arthritis (RA). However, its synovium‐related molecular mechanisms, particularly its regulatory effect on fibroblast‐like synoviocyte (FLS) migration, remain incompletely understood.
Shuqi Fang   +13 more
wiley   +1 more source

Growing Through It: A Longitudinal Examination of Body Dissatisfaction, Mental Health, and Resilience During Adolescence

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Introduction Research indicates adolescence, specifically puberty, is a critical period of psychological and physiological development. It is well known that body image is a key aspect of developmental psychology impacting mental health. Yet little is known about the buffering effects of resilience to moderate the relationship between body ...
Tiffany M. Stewart   +5 more
wiley   +1 more source

Chlorfenapyr Induces Hepatotoxicity Associated With Oxidative Stress and Mitochondrial Dysfunction Involving Keap1/Nrf2 Signaling

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Chlorfenapyr (CHL) is a widely used pyrrole insecticide, but its hepatotoxic effects and underlying mechanisms remain incompletely understood. This study investigated the toxic effects of CHL on rat liver and BRL‐3A hepatocytes and explored the involvement of the Keap1/Nrf2 signaling pathway. Rats were administered CHL (10, 20, or 30 mg/kg) by
Dongquan Zhao   +4 more
wiley   +1 more source

CHAPLE‐Like Enteropathy and Renal Microangiopathy in an Adult Patient With CD46 Deficiency

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
We report an adult patient with a homozygous CD46 variant presenting with lifelong protein‐losing enteropathy, intestinal lymphangiectasia, and CVID‐like hypogammaglobulinemia mimicking CHAPLE syndrome. Concurrent renal biopsy revealed PLA2R‐negative membranous nephropathy with chronic thrombotic microangiopathy, establishing multi‐organ complement ...
Bircan Erden   +14 more
wiley   +1 more source

Discrepant Urinary Findings Between Dipstick Protein and Sulfosalicylic Acid Test in a Patient With Hyaline Casts: A Case Report

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
In this post‐transplant patient, increased hyaline casts with negative dipstick protein but positive SSA testing occurred during evolving acute kidney injury and resolved with renal recovery. This discordant urinalysis pattern may warrant confirmatory protein testing and correlation with serial renal function in patients at high risk of AKI.
Yifei Jia   +6 more
wiley   +1 more source

“It All Exists Within Me”: A Qualitative Study Exploring Mental Health Service Experiences in Adults With Comorbid Eating Disorders and Emotionally Unstable Personality Disorder

open access: yesJournal of Clinical Psychology, EarlyView.
ABSTRACT Objective Comorbidity between Eating Disorders (ED) and Emotionally Unstable Personality Disorder (EUPD) is high. This comorbidity is also linked with worse outcomes for traditional evidence‐based treatments. We aimed to improve mental health service experience for adults with comorbid EUPD and ED by: (1) understanding the service‐user ...
Amy Lunn   +6 more
wiley   +1 more source

Iron‐modified natural sand as a heterogeneous Fenton catalyst for methylene blue and textile wastewater treatment

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND The continuous discharge of organic dyes into freshwater poses long‐term environmental risks. Heterogeneous Fenton‐like processes using iron (Fe)‐modified silica (SiO2) supports are promising for dye removal; however, catalysts derived from natural sand and operating under near‐neutral conditions remain relatively underexplored ...
Hajer Aloulou   +6 more
wiley   +1 more source

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