Results 51 to 60 of about 5,631,965 (202)

von Hippel-Lindau syndrome: analysis of multiple pathologies' connections

, 2023
reservedLa sindrome di von Hippel-Lindau, una rara malattia autosomica dominante, predispone l'individuo alla formazione di patologie multiple di natura sia benigna che maligna. La comprensione delle relazioni tra le diverse patologie manifestate risulta
BOSCOLO ANZOLETTI, AURORA
core  

Optimized Coherence Masking Improves Ultrasound Imaging of Kidney Cysts

Journal of Ultrasound in Medicine, EarlyView.
Objectives Renal cystic lesions are exceedingly common and typically benign, though accurate diagnostic techniques are required to recognize the subset of malignant lesions that require timely intervention. Ultrasound (US) is the preferred first line test for renal cyst evaluation because it is safe, widely accessible, and low cost. US imaging, however,
Scott Schoen Jr, Theodore T. Pierce, Sai Dhanush Reddy Jeggari, Abder‐Rhaman Ali, Kai E. Thomenius, Michael Wang, Brian Lause, Rimon Tadross, Kathleen Pope, David Hunt, Mary K. Peters, Mike Washburn, Anthony E. Samir   +12 more
wiley   +1 more source

SHP2 in Cancer: From Tumor Biology to Therapeutic Targeting

Medicinal Research Reviews, EarlyView.
ABSTRACT SHP2 is a tyrosine phosphatase that mediates intracellular signaling downstream of transmembrane receptors regulated by a pair of src homology 2 (SH2) domains. Its overexpression and mutation are pivotal in driving tumor progression by influencing various cancer's fundamental characteristics, such as metastasis, DNA repair, angiogenesis ...
Maryam Jama, Michael Overduin, Khaled H. Barakat   +2 more
wiley   +1 more source

Chronic high‐altitude exposure and intracerebral hemorrhage: A novel perspective from the vascular‐immune‐neuronal network

Neuroprotection, EarlyView.
Long‐term chronic high‐altitude hypobaric hypoxia increases susceptibility to ICH, particularly among migrant populations lacking EPAS1/SENP1 adaptive genetic variants relative to high‐altitude indigenous residents. Persistent hypoxia initiates blood–brain barrier (BBB) breakdown, aberrant glial and immune activation, and progressive neuronal injury ...
Rongsu Huang, Linjie Wei, Mingxi Li, Bo Wu, Rongjian Ouyang, Gang Zhu, Yujie Chen   +6 more
wiley   +1 more source

VHL (von Hippel-Lindau tumor suppressor) [PDF]

, 2002
Review on VHL (von Hippel-Lindau tumor suppressor), with data on DNA, on the protein encoded, and where the gene is ...
Richard, S
core   +1 more source

Spontaneous Rupture of a Small Chromophobe Renal Cell Carcinoma Presenting as Wunderlich Syndrome

IJU Case Reports, Volume 9, Issue 6, November 2026.
ABSTRACT Introduction Chromophobe renal cell carcinoma rarely causes spontaneous renal hemorrhage and enhances weakly on computed tomography. We report a case in which the tumor was masked by a perirenal hematoma for 11 months. Case Presentation A 46‐year‐old woman presented with spontaneous renal hemorrhage and no visible renal mass.
Naoki Kamimura, Ryohei Yamamoto, Yuya Sekine, Hiromi Sato, Mizuki Kobayashi, Mitsuru Saito, Shintaro Narita, Tomonori Habuchi   +7 more
wiley   +1 more source

Pancreatic Cysts Causing Biliary Obstruction in von Hippel Lindau Syndrome

, 2020
Context Extrahepatic biliary obstruction secondary to pancreatic cysts is rare in patients with von Hippel Lindau syndrome. We describe a patient with von Hippel Lindau syndrome who had biliary obstruction due to pancreatic cysts who was initially ...
Radha Krishan Dhiman, Ajay Duseja, Amod Gupta, Rahul Gupta, Yogesh Kumar Chawla, Arun Sharma, Arunanshu Behera, Deepak Chettri, Naveen Kalra   +8 more
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Von Hippel–Lindau Syndrome: A Case Report

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2009
BACKGROUND AND OBJECTIVE: Von Hippel–lindau syndrome is a rare syndrome. Von Hippel–Lindau is an autosomal dominant condition manifested by cerebellar and spinal hemangioblastomas, retinal angiomas, clear cell RCC, cysts of the pancreas, kidney, and ...
H Shafi,, M Rafati, B Ataee, A Ali Ramaji, AR Firoozjahi,, B Jahed   +5 more
doaj  

Genetic testing considerations for hereditary duodenopancreatic neuroendocrine tumors

Journal of Neuroendocrinology, Volume 38, Issue 11, November 2026.
Abstract The incidence of duodenal and pancreatic neuroendocrine tumors (dpNETs) has increased substantially in recent years. These tumors may be due to syndromic hereditary predisposition syndromes: multiple endocrine neoplasia type 1 (MEN1) or 4 (MEN4), Von Hippel–Lindau disease (VHL), neurofibromatosis type 1 (NF1), or tuberous sclerosis complex ...
Théo Charnay, Camille Giannetti, Nicolas Sahakian, Magalie Haissaguerre, Sandrine Oziel‐Taieb, Veronique Mari, Olivier Gilly, Pauline Vital, Isabelle Raingeard, Bénédicte Découdier, Alexandre Astier, Thomas Cuny, Pauline Romanet, Anne Barlier   +13 more
wiley   +1 more source

Spinal Hemangioblastomas in Von Hippel-Lindau Disease Mimicking a Spinal Dural Arteriovenous Fistula

Global Spine Journal, 2014
Introduction Spinal hemangioblastomas (HBs) are rare tumors that are closely associated with a diagnosis of Von Hippel-Lindau disease (VHL). A tissue diagnosis is needed to make the diagnosis of HB because many other entities can present similarly, which
J. Kalyvas, S. Change
doaj   +1 more source