Results 101 to 110 of about 185,950 (370)
Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: A new potential target for antifibrotic therapy [PDF]
, 2018 Background: Fibrosis may be considered the hallmark of systemic sclerosis (SSc), the end stage triggered by different pathological events. Transforming growth factor-β (TGF-β) and platelet-derived growth factor BB (PDGF-BB) are profibrotic molecules ...
Berardicurti O. +11 more
core +1 more source
Macromolecular Bioscience, EarlyView.The study investigates how four ECM‐mimicking biomaterials—fibrin, fibronectin, and non‐crosslinked or crosslinked gelatin—affect different types of human endothelial cells. Cell viability, morphology, and angiogenic marker expression are evaluated. Results reveal substrate‐dependent effects on cell behavior and emphasize the importance of selecting ...
Jernej Vajda +5 more
wiley +1 more source
Hemangiosarcoma of the third eyelid in a horse [PDF]
, 2009 A 12-year-old Belgian Warmblood mare was referred to the equine clinic of the Faculty of Veterinary Medicine (Ghent University) for a mass on the third eyelid of the right eye. The horse had been having a recurrent red-tinged ocular discharge for several
Chiers, Koen +4 more
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ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai +4 more
wiley +1 more source
Veterinary Record Case Reports, EarlyView.Abstract A 13‐year‐old dog with no history of spontaneous bleeding was presented for evaluation of multiple diffusely distributed cutaneous mast cell tumours. No obvious metastasis was found, and chemotherapy with vinblastine/lomustine was initiated. After the second dose of lomustine was administered, the dog experienced epistaxis for 2–3 minutes per ...
Andrew Schlueter, Rance Sellon
wiley +1 more source
Von willebrand disease: An overview
Indian Journal of Pharmaceutical Sciences, 2011 Most commonly inherited bleeding disorder, first described in Aland Islands by Erik von Willebrand. It occurs as a result of decrease in plasma levels or defect in von Willebrand factor which is a large multimeric glycoprotein. Monomers of this glycoprotein undergo N-glycosylation to form dimers which get arranged to give multimers. Binding with plasma
K Pavani Bharati, U Ram Prashanth
openaire +4 more sources
Laboratory aspects of von Willebrand disease: test repertoire and options for activity assays and genetic analysis [PDF]
, 2014 The deficiency or abnormal function of von Willebrand factor (VWF) causes von Willebrand disease (VWD), the most frequent inherited bleeding disorder. The laboratory diagnosis of VWD can be difficult as the disease is heterogeneous and an array of assays
Castaman, G., Goodeve, A., Hillarp, A.
core +1 more source
Wildlife Biology, EarlyView.Black grouse Lyrurus tetrix declines continue throughout much of temperate Europe, following habitat loss and population isolation, associated with reduced productivity. In northern England, only 1437 lekking males remained in 2014, genetically isolated from other UK populations, and typified by low productivity but high adult survival.
David Baines, Nicholas J. Aebischer
wiley +1 more source
Relation of morning serum cortisol to prothrombotic activity in women with stable coronary artery disease [PDF]
, 2018 Background: Increased circulating cortisol levels have been associated with severity of atherosclerosis. Low-grade systemic thrombogenicity plays a major role in the initiation and progression of coronary disease.
Kudielka, Brigitte +3 more
core
Fibrin D-dimer, markers of coagulation activation and the risk of major ischaemic heart disease in the Caerphilly Study [PDF]
, 2001 We have previously reported that plasma fibrin D-dimer (a marker of turnover of cross-linked Fibrin) showed a strong and independent association with incident ischaemic heart disease (IHD) in the Caerphilly Study cohort of 1,998 men a-ed 49-65.
Lowe, G.D.O. +4 more
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