Results 31 to 40 of about 185,950 (370)

Female case with misdiagnosis of hemophilia A who underwent total knee arthroplasty: A case report

Clinical Case Reports, 2022
A female was diagnosed with hemophilia A. She had undergone bilateral total knee arthroplasty. She had a history of numerous hemorrhages including hemarthrosis.
Alireza Bari, Hassan Mansouritorghabeh
doaj   +1 more source

An international survey to inform priorities for new guidelines on von Willebrand disease

Haemophilia, 2019
von Willebrand disease (VWD) is an inherited bleeding disorder caused by a quantitative or qualitative dysfunction of von Willebrand factor. Clinicians, patients and other stakeholders have many questions about the diagnosis and management of the disease.
Mohamad A. Kalot, M. Al-Khatib, Nathan T Connell, V. Flood, R. Brignardello-Petersen, P. James, R. Mustafa   +6 more
semanticscholar   +1 more source

Migraine and vascular disease biomarkers: A population-based case-control study. [PDF]

, 2018
Background The underpinnings of the migraine-stroke association remain uncertain, but endothelial activation is a potential mechanism. We evaluated the association of migraine and vascular disease biomarkers in a community-based population.
Ferrari, Michel D., Herial, Nabeel, Khubchandani, Jagdish, Koppen, Hille, Kruit, Mark C., Launer, Lenore J., Palm-Meinders, Inge H., Terwindt, Gisela M., Tietjen, Gretchen E., van Buchem, Mark A.   +9 more
core   +2 more sources

Biogenesis of Weibel-Palade bodies in von Willebrand’s disease variants with impaired von Willebrand factor intrachain or interchain disulfide bond formation

Haematologica, 2012
Background Mutations of cysteine residues in von Willebrand factor are known to reduce the storage and secretion of this factor, thus leading to reduced antigen levels. However, one cysteine mutation, p.Cys2773Ser, has been found in patients with type 2A(
Jiong-Wei Wang, Dafna J. Groeneveld, Guy Cosemans, Richard J. Dirven, Karine M. Valentijn, Jan Voorberg, Pieter H. Reitsma, Jeroen Eikenboom   +7 more
doaj   +1 more source

Case report: A case of acquired von Willebrand syndrome as onset clinical presentation of systemic lupus erythematosus manifested as epistaxis and pulmonary hemorrhage

Frontiers in Pediatrics, 2022
BackgroundAcquired von Willebrand syndrome (AVWS) is a less common bleeding disorder, primarily manifested as mild to moderate mucocutaneous bleeding and laboratory tests are similar to hereditary von Willebrand disease (VWD).
Songmi Wang, Qun Hu, Yaxian Chen, Xiufen Hu, Ning Tang, Ai Zhang, Aiguo Liu   +6 more
doaj   +1 more source

How I manage severe von Willebrand disease

British Journal of Haematology, 2019
Von Willebrand disease (VWD) is the most common inherited bleeding disorder. Most patients with mild and moderate VWD can be treated effectively with desmopressin.
F. Leebeek, F. Atiq
semanticscholar   +1 more source

Spontaneous iliopsoas muscle hematoma in a patient with von Willebrand disease: a case report

Journal of Medical Case Reports, 2011
Introduction Iliopsoas hemorrhage is a serious complication of bleeding disorders that occurs most commonly in patients with hemophilia and less commonly in patients with von Willebrand disease.
Soltani Shirazi Ahmad, Keikhaei Bijan
doaj   +1 more source

Phase 3 study of recombinant von Willebrand factor in patients with severe von Willebrand disease who are undergoing elective surgery

Journal of Thrombosis and Haemostasis, 2018
Essentials Recombinant von Willebrand factor (rVWF) is effective in von Willebrand disease (VWD). A phase 3 study of rVWF, with/without recombinant factor VIII (rFVIII) before surgery in VWD.
Flora Peyvandi, Flora Peyvandi, A. Mamaev, J.‐D. Wang, O. Stasyshyn, M. Timofeeva, Nicola Curry, Ana Rosa Cid, T. Yee, K. Kavakli, G. Castaman, A. Sytkowski   +11 more
semanticscholar   +1 more source

Closing the gap – detection of clinically relevant von Willebrand disease in emergency settings through an improved algorithm based on rotational Thromboelastometry

BMC Anesthesiology, 2019
Background Hemorrhage and blood loss are still among the main causes of preventable death. Global hemostatic assays are useful point-of-care test (POCT) devices to rapidly detect cumulative effects of plasma factors and platelets on coagulation ...
H.-G. Topf, E. R. Strasser, G. Breuer, W. Rascher, M. Rauh, F. B. Fahlbusch   +5 more
doaj   +1 more source

Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor. [PDF]

PLoS ONE, 2017
Adhesion of erythrocytes to endothelial cells lining the vascular wall can cause vaso-occlusive events that impair blood flow which in turn may result in ischemia and tissue damage.
Michel W J Smeets, Ruben Bierings, Henriet Meems, Frederik P J Mul, Dirk Geerts, Alexander P J Vlaar, Jan Voorberg, Peter L Hordijk   +7 more
doaj   +1 more source