Management of von Willebrand disease type 3 during pregnancy - 2 cases reports. [PDF]
, 2013 BACKGROUND: von Willebrand disease type 3, is an extremely rare condition. It can be severe and potentially life-threatening, particularly in pregnant women during labor and subsequently during early puerperium.
Azevedo, S. +3 more
core
Successful Aortic Aneurysm Repair in a Woman with Severe von Willebrand (Type 3) Disease
Case Reports in Hematology, 2015 von Willebrand disease type 3 (VWD3) is a rare but the most severe form of von Willebrand disease; it is due to almost complete lack of von Willebrand factor activity (VWF:RCo).
Victoria Campbell +3 more
doaj +1 more source
Advanced Science, EarlyView.This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu +18 more
wiley +1 more source
Preliminary Study Of Von Willebrand Factor Profiles Of The Different Abo Blood Group Among Malay Population [PDF]
, 2016 Di kalangan 28 juta penduduk Malaysia pada tahun 2010, sebanyak 0.002% pesakit von Willebrand dilaporkan dengan 63% daripadanya berbangsa Melayu.
Abdul Rahman, Rohaida
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ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis [PDF]
, 2005 Members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family are known to influence development, angiogenesis, coagulation and progression of arthritis.
Jones, GC, Riley, GP
core +2 more sources
Diagnostic Value of Measuring Platelet Von Willebrand Factor in Von Willebrand Disease. [PDF]
PLoS ONE, 2016 Von Willebrand disease (VWD) may be caused by an impaired von Willebrand factor (VWF) synthesis, its increased clearance or abnormal function, or combinations of these factors.
Alessandra Casonato +5 more
doaj +1 more source
Anti‐ADAMTS13 Antibodies Trajectory is Associated With ADAMTS13 Recovery in Immune‐Mediated TTP
American Journal of Hematology, EarlyView.Anti‐ADAMTS13 IgG antibodies titer trajectory from baseline to day 7–14 post‐TPE as a reliable approach to identify iTTP patients at risk of late response to the triplet therapy regimen. ABSTRACT Current triplet regimens associating therapeutic plasma exchange (TPE), immunosuppression with corticosteroids and rituximab, and caplacizumab have ...
Marie Robert +29 more
wiley +1 more source
Clinical surveillance of thrombotic microangiopathies in Scotland, 2003-2005 [PDF]
, 2007 The prevalence, incidence and outcomes of haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopaenic purpura (TTP) are not well established in adults or children from prospective studies. We sought to identify both outcomes and current management
D. YOUNG +8 more
core +2 more sources
The epitope of the antibody used in the REAADS VWF activity assay is quaternary
Thrombosis JournalThe REAADS VWF activity assay is often assumed to be specific for the A1 domain, the portion of VWF that binds platelet GPIbα. We tested this assay on the A1A2A3 region of VWF with each domain expressed independently of one another and together in ...
Alexander Tischer +2 more
doaj +1 more source
American Journal of Hematology, EarlyView.ABSTRACT Hereditary hemorrhagic telangiectasia (HHT, Osler‐Weber‐Rendu disease) is the second most common inherited bleeding disorder worldwide, affecting approximately 1 in 5000 people. Development of disease‐modifying and efficacious hemostatic agents to treat HHT has finally begun after decades without such medical therapies.
Hanny Al‐Samkari +22 more
wiley +1 more source