Results 31 to 40 of about 79,137 (303)
Research and Practice in Thrombosis and HaemostasisBackground: Hemorrhagic events in von Willebrand disease (VWD) impair patients’ physical health, daily functioning, and psychological/emotional well-being.
Annie Borel-Derlon +15 more
doaj +1 more source
Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor. [PDF]
PLoS ONE, 2017 Adhesion of erythrocytes to endothelial cells lining the vascular wall can cause vaso-occlusive events that impair blood flow which in turn may result in ischemia and tissue damage.
Michel W J Smeets +7 more
doaj +1 more source
Treatment of Von Willebrand Disease [PDF]
Thrombosis and Haemostasis, 1998 SummaryIn von Willebrand disease, there are two main options for the treatment of spontaneous bleeding episodes and for bleeding prophylaxis: desmopressin and transfusional therapy with plasma products. Desmopressin is the treatment of choice for most patients with type 1, who account for approximately 70 to 80 per cent of all cases with the disease ...
C. A. Lee +5 more
openaire +6 more sources
Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria [PDF]
, 2014 Systemic inflammation and sequestration of parasitized erythrocytes are central processes in the pathophysiology of severe Plasmodium falciparum childhood malaria. However, it is still not understood why some children are more at risks to develop malaria
Afolabi, Nathaniel K. +19 more
core +3 more sources
Научно-практическая ревматология, 2004 Objective. To determine the importance of von Willebrand factor antigen as marker of endotheliae damage at the patients with systemic lupus erythematosus (SLE). Material and methods. 30 women from authentic SLE by criteria ACR, in the age of 20-45 years,
M E Zapryagaeva, E S Mach, A A Baranov
doaj +1 more source
Infection frequently triggers thrombotic microangiopathy in patients with preexisting risk factors : a single-institution experience [PDF]
, 2010 Thrombotic microangiopathies are rare conditions characterized by microangiopathic hemolytic anemia, microthrombi, and multiorgan insult. The disorders, which include hemolytic uremic syndrome and thrombotic thrombocytopenic purpura, are often acute and ...
Catlow, Jamie +4 more
core +1 more source
Analysis of von Willebrand Disease in the “Heart of Europe”
TH Open, 2022 Background von Willebrand disease (VWD) is a genetic bleeding disorder caused by defects of von Willebrand factor (VWF), quantitative (type 1 and 3) or qualitative (type 2). The laboratory phenotyping is heterogenic making diagnosis difficult.
Inge Vangenechten +11 more
doaj +1 more source
Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs [PDF]
, 2017 Increases in prothrombin time (PT) and international normalised ratio (INR) characterise acute liver injury (ALI) and failure (ALF), yet a wide heterogeneity in clotting abnormalities exists.
A Clauss +39 more
core +4 more sources
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Advanced Healthcare Materials, EarlyView.Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Successful Aortic Aneurysm Repair in a Woman with Severe von Willebrand (Type 3) Disease
Case Reports in Hematology, 2015 von Willebrand disease type 3 (VWD3) is a rare but the most severe form of von Willebrand disease; it is due to almost complete lack of von Willebrand factor activity (VWF:RCo).
Victoria Campbell +3 more
doaj +1 more source