Results 71 to 80 of about 36,491 (170)

Haemophilia Prophylaxis in the Age of Innovation: Exploring Opportunities for Personalized Treatment

Haemophilia, EarlyView.
ABSTRACT Introduction Recent advancements in haemophilia treatment have introduced a range of innovative therapies, including activated FVIII mimetics, ultra‐extended half‐life recombinant FVIII, rebalancing agents and gene therapy. These developments have transformed treatment options and expanded prophylaxis strategies.
Yesim Dargaud, Fabienne Volot, Stephanie Desage, Claire Pouplard, Valerie Chamouard, Anne Lienhart   +5 more
wiley   +1 more source

High Prevalence of Platelet Function Disorders in Women Referred for Surgical Management of Refractory Heavy Menstrual Bleeding

Haemophilia, EarlyView.
ABSTRACT Introduction Heavy menstrual bleeding (HMB) is a common presenting symptom in women with bleeding disorders, yet haemostatic testing is sometimes overlooked, even when refractory HMB requires surgical intervention. Aim To determine the prevalence of bleeding disorders in women referred for surgical management of HMB and investigate screening ...
Alison Delaney, Evangelos I. Kritsotakis, Kevin Horner, Steve Kitchen, Jennifer Sedcole, Ted Baxter, Rhona M. Maclean, Michael Makris, Clare V. Samuelson   +8 more
wiley   +1 more source

Ratio of Von Willebrand Collagen Binding Assay and Von Willebrand Antigen Can Predict Multimer Size in Von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Background Von Willebrand disease (vWD) is a common bleeding disorder with different subtypes. Laboratory diagnosis is challenging, involving several expensive and complex assays. The von Willebrand factor (vWF) collagen binding assay (VWF:CB) has been described to improve the diagnosis of vWD, but there is a lack of consensus and its ...
Adrian Kimiaei, Iva Pruner, Maria Farm, Margareta Holmström, Natali Karandyszowska, Maria Bruzelius, Jovan Antovic, Anna Ågren   +7 more
wiley   +1 more source

The Use of Primary Care Physiotherapy for Persons With Bleeding Disorders in the Netherlands–A Retrospective Study of Health Records

Haemophilia, EarlyView.
ABSTRACT Introduction Patients with musculoskeletal complaints as a result of their bleeding disorder can benefit from primary care physiotherapy. The current study aims to describe physiotherapy services provided in primary care to patients with bleeding disorders and to what extent treatment was already in concordance with treatment recommendations ...
Johan Blokzijl, Martijn F. Pisters, Cindy Veenhof, Roger E. G. Schutgens, Merel A. Timmer   +4 more
wiley   +1 more source

Subjective Physical Performance and Its Determinants in Patients With Haemophilia

Haemophilia, EarlyView.
ABSTRACT Introduction Physical functioning is compromised in patients with haemophilia (PwH). However, factors negatively influencing subjective physical performance (SPP) remain underexplored. Hence, this study aimed to compare the SPP of PwH with healthy controls (CON), to differentiate them based on disease‐specific, person‐related, and arthropathy ...
Alexander Schmidt, Fabian Tomschi, Pia Möllers, Marius Brühl, Sylvia von Mackensen, Andreas C. Strauss, Heinrich Richter, Johannes Oldenburg, Thomas Hilberg   +8 more
wiley   +1 more source

Physical Activity Awareness and Understanding of Treatment Protection Among People With Haemophilia and Their Caregivers in Central Europe

Haemophilia, EarlyView.
ABSTRACT Background Physical activity is now considered generally beneficial for persons with haemophilia (PWH). However, the specific type and extent of activity and its impact on quality of life (QoL) and bleed protection during exercise is under‐researched.
Angelika Batorova, Atanas Banchev, Ana Boban, Brigitte Brand, Melen Brinza, Barbara Faganel Kotnik, Csongor Kiss, Gediminas Puras, Jan Rajnoch, Ester Zapotocka   +9 more
wiley   +1 more source

European Principles of Nursing Care for Persons With Inherited Bleeding Disorders

Haemophilia, EarlyView.
ABSTRACT Introduction A nurse is one of the core members of the multidisciplinary haemophilia team. However, what people with inherited bleeding disorders (PwBD) can expect from them has not yet been formally defined. Aim This project, initiated by the EAHAD Nurses Committee, aimed to establish Principles of Nursing Care (PoNC) for PwBD to promote high‐
Nanda Uitslager, Mary Kavanagh, Maj Birkedal, Linda Myrin‐Westesson, the EAHAD Nurses Committee   +4 more
wiley   +1 more source

Weibel-Palade body formation and exocytosis in von Willebrand disease [PDF]

, 2013
The studies presented in this thesis explored several pathogenic mechanisms underlying von Willebrand disease that is characterized by a quantitative or functional deficiency of von Willebrand factor, in particular with respect to intracellular storage ...
Wang, J.W.
core   +1 more source

Outcomes of Dental Treatment Procedures in People With Haemophilia Treated Under a Comprehensive Care Model: An Analysis of Cases From a Tertiary Care Centre

Haemophilia, EarlyView.
ABSTRACT Background Haemophilia is a chronic, lifelong bleeding disorder that requires interdisciplinary care to manage and mitigate the disease burden throughout a patient's life. There is no universally accepted protocol for managing haemophilia patients during dental care.
Mathangi Kumar, Sulochana Badagabettu, Keerthilatha M. Pai, Annamma Kurien, Archana MV, Shreemathi S. Mayya, Sreejith Govindan   +6 more
wiley   +1 more source

Relation of morning serum cortisol to prothrombotic activity in women with stable coronary artery disease [PDF]

, 2018
Background: Increased circulating cortisol levels have been associated with severity of atherosclerosis. Low-grade systemic thrombogenicity plays a major role in the initiation and progression of coronary disease.
Kudielka, Brigitte, Mausbach, Brent, Orth-Gomér, Kristina, von Känel, Roland   +3 more
core