Results 81 to 90 of about 146,739 (334)

Refractory anaemia in a patient with end‐stage heart failure secondary to aortic stenosis

ESC Heart Failure, EarlyView.
Jiayu Liang, Suxin Luo, Bi Huang
wiley   +1 more source

Quantitative Systems Pharmacology Modeling of Platelet Responses to Recombinant ADAMTS13 in Patients With Congenital Thrombotic Thrombocytopenic Purpura

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra‐rare, life‐threatening thrombotic microangiopathy caused by a severe inherited deficiency of ADAMTS13, a von Willebrand factor (VWF) cleaving enzyme. Inadequate clinical endpoint data often make it challenging to statistically power clinical trials in ultra‐rare diseases ...
Cameron McBride, Jiaolong Jiang, Zhiwei Zhang, John Tolsma, Parth Patwari, Björn Mellgård, Majid Vakilynejad, Indranil Bhattacharya, Andy Z. X. Zhu   +8 more
wiley   +1 more source

Choroba von Willebranda – najczęstsza osoczowa skaza krwotoczna

Menopause Review, 2010
Von Willebrand disease is the most common hereditary haemorrhagic disorder. A majority of patients (70%)have classic mild or moderate (type I) von Willebrand disease, and women are mostly affected.
Bożena Sokołowska
doaj  

How I treat type 2 variant forms of von Willebrand disease.

Blood, 2015
Type 2 von Willebrand disease (VWD) includes a wide range of qualitative abnormalities of von Willebrand factor structure and function resulting in a variable bleeding tendency.
A. Tosetto, G. Castaman
semanticscholar   +1 more source

Laminar Flow Alters EV Composition in HUVECs: A Study of Culture Medium Optimization and Molecular Profiling of Vesicle Cargo

Small Methods, EarlyView.
Schematic illustration of the current study. A) Multiple cell culture media are used for HUVEC cultures under both static and flow conditions. Cells are analyzed for morphology, endothelial markers, and gene expression. B) EVs are isolated from static and flow HUVEC cultures, and investigated for particle characterization, transcriptome and proteome ...
Arefeh Kardani, Jan Hemmer, Britta Diesel, Vida Mashayekhi, Annika Schomisch, Marcus Koch, Claudia Fecher‐Trost, Markus R Meyer, Nicole Ludwig, Shusruto Rishik, Andreas Keller, Jessica Hoppstädter, Gregor Fuhrmann, Alexandra K. Kiemer   +13 more
wiley   +1 more source

Prophylaxis escalation in severe von Willebrand disease: a prospective study from the von Willebrand Disease Prophylaxis Network

Journal of Thrombosis and Haemostasis, 2015
Treatment of mucosal bleeding (epistaxis, gastrointestinal bleeding, and menorrhagia) and joint bleeding remains problematic in clinically severe von Willebrand disease (VWD). Patients are often unresponsive to treatment (e.g.
T. Abshire, J. Cox-Gill, C. Kempton, F. Leebeek, M. Carcao, P. Kouides, S. Donfield, E. Berntorp   +7 more
semanticscholar   +1 more source

Plasma POSTN Derived From Bile Proteome Is a Promising Biomarker for Cholangiocarcinoma With Efficacy Comparable and Complementary to CA19.9

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background Cholangiocarcinoma presents a global health challenge due to its increasing incidence and poor prognosis, primarily resulting from delayed diagnosis. There is an urgent need for a reliable biomarker to enhance early detection. Materials and Methods Patients with cholangiocarcinoma were enrolled into three cohorts: a discovery set (n 
Lichieh Julie Chu, Chia‐Jung Tsai, Chun‐Chun Chien, Yung‐Chin Hsiao, Jau‐Song Yu, Jun‐Yi Tsai, Ta‐Sen Yeh   +6 more
wiley   +1 more source

A new drug for an old concept: aptamer to von Willebrand factor for prevention of arterial and microvascular thrombosis

Haematologica, 2020
Agnès Veyradier
doaj   +1 more source

Platelet factor VIII-related antigen: studies in vivo after transfusion in patients with von Willebrand disease [PDF]

, 1978
Y Sultan, C. Jeanneau, J.-M. D. Lamaziere, Patrick Maisonneuve, JP Caen   +4 more
openalex   +1 more source

Menstrual suppression to decrease intrauterine device expulsion in adolescents with inherited bleeding disorders

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 421-423, April 2025.
Peter H. Cygan, Kelly M. Kons, Megan H. Fiorillo, Tonya S. Wright   +3 more
wiley   +1 more source